Growth and Neurodevelopmental Outcome in Preterm LBW Infants with Sepsis in India: A Prospective Cohort
Objective. Neonatal sepsis is associated with abnormal neurodevelopmental outcomes but not with poor growth at 9 to 15 months of corrected age in LBW infants. Design, Setting, and Participants. This is a prospective cohort study involving 128 eligible preterm low-birth-weight (LBW) infants admitted...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | International Journal of Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2018/5735632 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832559024356196352 |
|---|---|
| author | Sunil J. Pawar Tejopratap Oleti Siluvery Bharathi Shyamsunder Tipparaju Ershad Mustafa |
| author_facet | Sunil J. Pawar Tejopratap Oleti Siluvery Bharathi Shyamsunder Tipparaju Ershad Mustafa |
| author_sort | Sunil J. Pawar |
| collection | DOAJ |
| description | Objective. Neonatal sepsis is associated with abnormal neurodevelopmental outcomes but not with poor growth at 9 to 15 months of corrected age in LBW infants. Design, Setting, and Participants. This is a prospective cohort study involving 128 eligible preterm low-birth-weight (LBW) infants admitted during the period of 2013-2014 to the Durgabai Deshmukh Hospital and Research Center. All patients were followed up in the outpatient Department of Pediatrics. They were divided into the sepsis and nonsepsis group. Results. A total of 94 infants were evaluated (40 in sepsis and 54 in nonsepsis group). At the age of 9–15 months, low-birth-weight infants with neonatal sepsis had an increased risk of neurodevelopmental disorders (67.5 versus 20.3%; RR: 3.31 (1.87–5.85)). There is no statistically significant difference in the growth outcomes. Conclusion. Neonatal infections are associated with the abnormal neurodevelopmental outcomes in LBW infants but there was no significant difference at growth outcome at 9 to 15 months of corrected age between both groups. |
| format | Article |
| id | doaj-art-b0486ed81e594f18b7f99388c828d0c5 |
| institution | Kabale University |
| issn | 1687-9740 1687-9759 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj-art-b0486ed81e594f18b7f99388c828d0c52025-02-03T01:31:03ZengWileyInternational Journal of Pediatrics1687-97401687-97592018-01-01201810.1155/2018/57356325735632Growth and Neurodevelopmental Outcome in Preterm LBW Infants with Sepsis in India: A Prospective CohortSunil J. Pawar0Tejopratap Oleti1Siluvery Bharathi2Shyamsunder Tipparaju3Ershad Mustafa4Durgabai Deshmukh Hospital and Research Center, Hyderabad, IndiaFernandez Hospital, Hyderabad, IndiaDurgabai Deshmukh Hospital and Research Center, Hyderabad, IndiaThumbay Hospital New Life, Hyderabad, IndiaDurgabai Deshmukh Hospital and Research Center, Hyderabad, IndiaObjective. Neonatal sepsis is associated with abnormal neurodevelopmental outcomes but not with poor growth at 9 to 15 months of corrected age in LBW infants. Design, Setting, and Participants. This is a prospective cohort study involving 128 eligible preterm low-birth-weight (LBW) infants admitted during the period of 2013-2014 to the Durgabai Deshmukh Hospital and Research Center. All patients were followed up in the outpatient Department of Pediatrics. They were divided into the sepsis and nonsepsis group. Results. A total of 94 infants were evaluated (40 in sepsis and 54 in nonsepsis group). At the age of 9–15 months, low-birth-weight infants with neonatal sepsis had an increased risk of neurodevelopmental disorders (67.5 versus 20.3%; RR: 3.31 (1.87–5.85)). There is no statistically significant difference in the growth outcomes. Conclusion. Neonatal infections are associated with the abnormal neurodevelopmental outcomes in LBW infants but there was no significant difference at growth outcome at 9 to 15 months of corrected age between both groups.http://dx.doi.org/10.1155/2018/5735632 |
| spellingShingle | Sunil J. Pawar Tejopratap Oleti Siluvery Bharathi Shyamsunder Tipparaju Ershad Mustafa Growth and Neurodevelopmental Outcome in Preterm LBW Infants with Sepsis in India: A Prospective Cohort International Journal of Pediatrics |
| title | Growth and Neurodevelopmental Outcome in Preterm LBW Infants with Sepsis in India: A Prospective Cohort |
| title_full | Growth and Neurodevelopmental Outcome in Preterm LBW Infants with Sepsis in India: A Prospective Cohort |
| title_fullStr | Growth and Neurodevelopmental Outcome in Preterm LBW Infants with Sepsis in India: A Prospective Cohort |
| title_full_unstemmed | Growth and Neurodevelopmental Outcome in Preterm LBW Infants with Sepsis in India: A Prospective Cohort |
| title_short | Growth and Neurodevelopmental Outcome in Preterm LBW Infants with Sepsis in India: A Prospective Cohort |
| title_sort | growth and neurodevelopmental outcome in preterm lbw infants with sepsis in india a prospective cohort |
| url | http://dx.doi.org/10.1155/2018/5735632 |
| work_keys_str_mv | AT suniljpawar growthandneurodevelopmentaloutcomeinpretermlbwinfantswithsepsisinindiaaprospectivecohort AT tejopratapoleti growthandneurodevelopmentaloutcomeinpretermlbwinfantswithsepsisinindiaaprospectivecohort AT siluverybharathi growthandneurodevelopmentaloutcomeinpretermlbwinfantswithsepsisinindiaaprospectivecohort AT shyamsundertipparaju growthandneurodevelopmentaloutcomeinpretermlbwinfantswithsepsisinindiaaprospectivecohort AT ershadmustafa growthandneurodevelopmentaloutcomeinpretermlbwinfantswithsepsisinindiaaprospectivecohort |