Naltriben promotes tumor growth by activating the TRPM7-mediated development of the anti-inflammatory M2 phenotype
Abstract Macrophage plasticity is critical for maintaining immune function and developing solid tumors; however, the macrophage polarization mechanism remains incompletely understood. Our findings reveal that Mg2+ entry through distinct plasma membrane channels is critical to macrophage plasticity....
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Main Authors: | Viviane Nascimento Da Conceicao, Yuyang Sun, Manigandan Venkatesan, Jorge De La Chapa Chapa, Karthik Ramachandran, Rahul S. Jasrotia, Victor Drel, Xiufang Chai, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | npj Precision Oncology |
Online Access: | https://doi.org/10.1038/s41698-025-00815-x |
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