The multifaceted impact of physical exercise on FoxO signaling pathways

The multifaceted impact of physical exercise on FoxO signaling pathways

This review explores the multifaceted impact of physical exercise on FoxO signaling pathways, which play a central role in cellular homeostasis, stress response, metabolism, and longevity. Exercise influences FoxO proteins—particularly FoxO1, FoxO3, FoxO4, and FoxO6—through diverse mechanisms, inclu...

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Bibliographic Details
Main Authors: Wei Liu, Pengjun Meng, Zhi Li, Yifei Shen, Xin Meng, Shen Jin, Mengdi Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
FoxO signaling pathways
physical exercise
metabolic regulation
skeletal muscle
complex
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1614732/full
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https://www.frontiersin.org/articles/10.3389/fcell.2025.1614732/full

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