Multi-omics integration identifies key biomarkers in retinopathy of prematurity through 16S rRNA sequencing and metabolomics

Multi-omics integration identifies key biomarkers in retinopathy of prematurity through 16S rRNA sequencing and metabolomics

BackgroundThe gut microbiome is increasingly recognized for its role in the pathogenesis of neonatal conditions commonly associated with retinopathy of prematurity (ROP). This study aimed to identify key intestinal microbiota and metabolites in ROP and examine their relationships.MethodsFecal sample...

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Bibliographic Details
Main Authors: Linlin Guo, Ruoming Wang, Liping Han, Yongcheng Fu, Xiujuan Wang, Lintao Nie, Wenjun Fu, Hongyan Ren, Lijia Wu, Guangshuai Li, Juan Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Microbiology
Subjects:
retinopathy of prematurity
differential intestinal floral
differentially accumulated metabolites
multi-omics integration
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1601292/full
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