Cannabidiol reduces synaptic strength and neuronal firing in layer V pyramidal neurons of the human cortex with drug-resistant epilepsy

Cannabidiol reduces synaptic strength and neuronal firing in layer V pyramidal neurons of the human cortex with drug-resistant epilepsy

The use of cannabidiol (CBD) as an alternative pharmacological approach for the symptomatic management of epilepsy has gained attention due to its potential efficacy, particularly in drug-resistant cases of epilepsy. Although multiple studies have described that CBD reduces neuronal hyperexcitabilit...

Full description

Saved in:
Bibliographic Details
Main Authors: Vladimir A. Martinez-Rojas, Luis A. Márquez, Christopher Martinez-Aguirre, Isabel Sollozo-Dupont, Félix Iván López Preza, Monserrat Fuentes Mejía, Mario Alonso, Luisa Rocha, Emilio J. Galván
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
cannabidiol
human cortex
layer V pyramidal neuron
patch-clamp recordings
ion channels
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1627465/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items