Obstructive Jaundice as an Initial Manifestation of Non-Hodgkin Lymphoma: Treatment Dilemma and High Mortality
Introduction. Non Hodgkin lymphoma (NHL) presenting with obstructive jaundice is a rare occurrence. Because of rarity of combination, it is seldom considered in differential diagnosis of patients presenting with obstructive jaundice. It is considered treatable due to the chemosensitive nature of the...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/259642 |
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| author | Dhara Chaudhari Sarah Khan Atif Saleem Tamarro Taylor Chakradhar Reddy Thomas Borthwick Mark Young |
| author_facet | Dhara Chaudhari Sarah Khan Atif Saleem Tamarro Taylor Chakradhar Reddy Thomas Borthwick Mark Young |
| author_sort | Dhara Chaudhari |
| collection | DOAJ |
| description | Introduction. Non Hodgkin lymphoma (NHL) presenting with obstructive jaundice is a rare occurrence. Because of rarity of combination, it is seldom considered in differential diagnosis of patients presenting with obstructive jaundice. It is considered treatable due to the chemosensitive nature of the disease and the recent advances in chemotherapy. Case Series. We present a case series of 2 patients with NHL presenting with obstructive jaundice as an initial manifestation. Both patients presented with obstructive jaundice and were diagnosed by CT guided liver biopsy. One patient died of sepsis and multiorgan failure before initiating chemotherapy and the second patient did not choose to undergo chemotherapy. Conclusion. Biliary obstruction is a sign of poor prognosis. The diagnosis of NHL needs to be considered in patients presenting with biliary obstruction. It can be associated with high mortality and poses treatment dilemma. |
| format | Article |
| id | doaj-art-b016b74bc5314865afeed0c6b81bdec7 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-b016b74bc5314865afeed0c6b81bdec72025-02-03T01:04:55ZengWileyCase Reports in Medicine1687-96271687-96352013-01-01201310.1155/2013/259642259642Obstructive Jaundice as an Initial Manifestation of Non-Hodgkin Lymphoma: Treatment Dilemma and High MortalityDhara Chaudhari0Sarah Khan1Atif Saleem2Tamarro Taylor3Chakradhar Reddy4Thomas Borthwick5Mark Young6Department of Internal Medicine, East Tennessee State University, Quillen College of Medicine, P.O. Box 70622, Johnson City, TN 37614, USADepartment of Internal Medicine, East Tennessee State University, Quillen College of Medicine, P.O. Box 70622, Johnson City, TN 37614, USADepartment of Gastroenterology, East Tennessee State University, Quillen College of Medicine, Johnson City, TN 37614, USADepartment of Oncology, VA Medical Center, Quillen College of Medicine, Mountain Home, TN 37684, USADepartment of Gastroenterology, East Tennessee State University, Quillen College of Medicine, Johnson City, TN 37614, USADepartment of Gastroenterology, East Tennessee State University, Quillen College of Medicine, Johnson City, TN 37614, USADepartment of Gastroenterology, East Tennessee State University, Quillen College of Medicine, Johnson City, TN 37614, USAIntroduction. Non Hodgkin lymphoma (NHL) presenting with obstructive jaundice is a rare occurrence. Because of rarity of combination, it is seldom considered in differential diagnosis of patients presenting with obstructive jaundice. It is considered treatable due to the chemosensitive nature of the disease and the recent advances in chemotherapy. Case Series. We present a case series of 2 patients with NHL presenting with obstructive jaundice as an initial manifestation. Both patients presented with obstructive jaundice and were diagnosed by CT guided liver biopsy. One patient died of sepsis and multiorgan failure before initiating chemotherapy and the second patient did not choose to undergo chemotherapy. Conclusion. Biliary obstruction is a sign of poor prognosis. The diagnosis of NHL needs to be considered in patients presenting with biliary obstruction. It can be associated with high mortality and poses treatment dilemma.http://dx.doi.org/10.1155/2013/259642 |
| spellingShingle | Dhara Chaudhari Sarah Khan Atif Saleem Tamarro Taylor Chakradhar Reddy Thomas Borthwick Mark Young Obstructive Jaundice as an Initial Manifestation of Non-Hodgkin Lymphoma: Treatment Dilemma and High Mortality Case Reports in Medicine |
| title | Obstructive Jaundice as an Initial Manifestation of Non-Hodgkin Lymphoma: Treatment Dilemma and High Mortality |
| title_full | Obstructive Jaundice as an Initial Manifestation of Non-Hodgkin Lymphoma: Treatment Dilemma and High Mortality |
| title_fullStr | Obstructive Jaundice as an Initial Manifestation of Non-Hodgkin Lymphoma: Treatment Dilemma and High Mortality |
| title_full_unstemmed | Obstructive Jaundice as an Initial Manifestation of Non-Hodgkin Lymphoma: Treatment Dilemma and High Mortality |
| title_short | Obstructive Jaundice as an Initial Manifestation of Non-Hodgkin Lymphoma: Treatment Dilemma and High Mortality |
| title_sort | obstructive jaundice as an initial manifestation of non hodgkin lymphoma treatment dilemma and high mortality |
| url | http://dx.doi.org/10.1155/2013/259642 |
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