Classification of diabetes: a new view on the problem
Diabetes mellitus is one of the main problems of modern medicine, which is primarily due to the high risk of developing cardiovascular complications in patients, as well as their early disability and mortality. The progressive increase in the number of patients with diabetes mellitus and high mortal...
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| Format: | Article |
| Language: | Russian |
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Open Systems Publication
2022-07-01
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| Series: | Лечащий Врач |
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| Online Access: | https://journal.lvrach.ru/jour/article/view/932 |
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| author | L. A. Kudentsova D. V. Davydov S. V. Chernavsky A. A. Stremoukhov |
| author_facet | L. A. Kudentsova D. V. Davydov S. V. Chernavsky A. A. Stremoukhov |
| author_sort | L. A. Kudentsova |
| collection | DOAJ |
| description | Diabetes mellitus is one of the main problems of modern medicine, which is primarily due to the high risk of developing cardiovascular complications in patients, as well as their early disability and mortality. The progressive increase in the number of patients with diabetes mellitus and high mortality among them dictate the need for further study of the causes and mechanisms of the development of the disease. Despite the availability of modern diagnostic methods, as well as the development of new therapeutic and preventive measures, the number of cases of early disability and mortality continues to increase among people with diabetes mellitus of working age. The main reason for such outcomes is the development of chronic cardiovascular complications. Evaluation of modern aspects of the etiology and pathogenesis of carbohydrate metabolism disorders will allow developing more effective methods for diagnosing, treating and preventing the development of complications in patients with diabetes mellitus. Despite more than a century of history of the study of diabetes mellitus, our knowledge of the pathogenesis of the disease is constantly supplemented by new links. The pathogenesis of diabetes mellitus is a multifaceted process. The modern classification of diabetes mellitus is based on some links of pathogenesis and determines its therapy. A number of authors have presented a cluster approach of types of diabetes mellitus, reflecting not only the links of pathogenesis, but also the risk of developing chronic complications. There are 5 clusters of the disease in total: SAID, SIDD, SARD, MOD, MARD. We studied 1120 case histories of patients with diabetes mellitus, determined the frequency of occurrence of its clusters and estimated the prognosis of chronic complications. At the same time, it was found that diabetic retinopathy was most common in the clusters SAID, SIDD, MOD. Along with this, diabetic nephropathy was characteristic of SAID, SIDD, SIRD, and distal polyneuropathy was characteristic of SIDD. Individuals with the MARD cluster were more likely to develop macroangiopathy of the lower extremities. The identification and study of clusters of diabetes mellitus contributes to the optimization of therapeutic and preventive measures. |
| format | Article |
| id | doaj-art-afde0fc8599245b3bc52a96ade1253fd |
| institution | DOAJ |
| issn | 1560-5175 2687-1181 |
| language | Russian |
| publishDate | 2022-07-01 |
| publisher | Open Systems Publication |
| record_format | Article |
| series | Лечащий Врач |
| spelling | doaj-art-afde0fc8599245b3bc52a96ade1253fd2025-08-20T02:49:01ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812022-07-0105-6849010.51793/OS.2022.25.6.015927Classification of diabetes: a new view on the problemL. A. Kudentsova0D. V. Davydov1S. V. Chernavsky2A. A. Stremoukhov3Federal State Budgetary Institution Main Military Clinical Hospital named after Academician N. N. Burdenko Ministry of Defense of the Russian FederationFederal State Budgetary Institution Main Military Clinical Hospital named after Academician N. N. Burdenko Ministry of Defense of the Russian Federation; Federal State Autonomous Educational Institution of Higher Education Peoples' Friendship University of RussiaFederal State Budgetary Institution Main Military Clinical Hospital named after Academician N. N. Burdenko Ministry of Defense of the Russian Federation; Federal State Budgetary Educational Institution of Additional Professional Education Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian FederationFederal State Autonomous Educational Institution of Higher Education Peoples' Friendship University of RussiaDiabetes mellitus is one of the main problems of modern medicine, which is primarily due to the high risk of developing cardiovascular complications in patients, as well as their early disability and mortality. The progressive increase in the number of patients with diabetes mellitus and high mortality among them dictate the need for further study of the causes and mechanisms of the development of the disease. Despite the availability of modern diagnostic methods, as well as the development of new therapeutic and preventive measures, the number of cases of early disability and mortality continues to increase among people with diabetes mellitus of working age. The main reason for such outcomes is the development of chronic cardiovascular complications. Evaluation of modern aspects of the etiology and pathogenesis of carbohydrate metabolism disorders will allow developing more effective methods for diagnosing, treating and preventing the development of complications in patients with diabetes mellitus. Despite more than a century of history of the study of diabetes mellitus, our knowledge of the pathogenesis of the disease is constantly supplemented by new links. The pathogenesis of diabetes mellitus is a multifaceted process. The modern classification of diabetes mellitus is based on some links of pathogenesis and determines its therapy. A number of authors have presented a cluster approach of types of diabetes mellitus, reflecting not only the links of pathogenesis, but also the risk of developing chronic complications. There are 5 clusters of the disease in total: SAID, SIDD, SARD, MOD, MARD. We studied 1120 case histories of patients with diabetes mellitus, determined the frequency of occurrence of its clusters and estimated the prognosis of chronic complications. At the same time, it was found that diabetic retinopathy was most common in the clusters SAID, SIDD, MOD. Along with this, diabetic nephropathy was characteristic of SAID, SIDD, SIRD, and distal polyneuropathy was characteristic of SIDD. Individuals with the MARD cluster were more likely to develop macroangiopathy of the lower extremities. The identification and study of clusters of diabetes mellitus contributes to the optimization of therapeutic and preventive measures.https://journal.lvrach.ru/jour/article/view/932diabetes mellituspathogenesis of diabetes mellitusclassification of diabetes mellitusclusterscomplications of diabetes mellitusprognosis of the course of diabetes mellitus |
| spellingShingle | L. A. Kudentsova D. V. Davydov S. V. Chernavsky A. A. Stremoukhov Classification of diabetes: a new view on the problem Лечащий Врач diabetes mellitus pathogenesis of diabetes mellitus classification of diabetes mellitus clusters complications of diabetes mellitus prognosis of the course of diabetes mellitus |
| title | Classification of diabetes: a new view on the problem |
| title_full | Classification of diabetes: a new view on the problem |
| title_fullStr | Classification of diabetes: a new view on the problem |
| title_full_unstemmed | Classification of diabetes: a new view on the problem |
| title_short | Classification of diabetes: a new view on the problem |
| title_sort | classification of diabetes a new view on the problem |
| topic | diabetes mellitus pathogenesis of diabetes mellitus classification of diabetes mellitus clusters complications of diabetes mellitus prognosis of the course of diabetes mellitus |
| url | https://journal.lvrach.ru/jour/article/view/932 |
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