Getting to the Heart of the Matter: Exploring the Intersection of Cardiovascular Disease, Sex and Race and How Exercise, and Gut Microbiota Influence these Relationships

Cardiovascular disease (CVD) is the leading cause of death worldwide, with physical inactivity being a known contributor to the global rates of CVD incidence. CVD incidence, however, is not uniform with recognized sex differences as well and racial and ethnic differences. Furthermore, gut microbiota...

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Main Authors: John J. Guers, Kevin S. Heffernan, Sara C. Campbell
Format: Article
Language:English
Published: IMR Press 2025-02-01
Series:Reviews in Cardiovascular Medicine
Subjects:
Online Access:https://www.imrpress.com/journal/RCM/26/2/10.31083/RCM26430
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author John J. Guers
Kevin S. Heffernan
Sara C. Campbell
author_facet John J. Guers
Kevin S. Heffernan
Sara C. Campbell
author_sort John J. Guers
collection DOAJ
description Cardiovascular disease (CVD) is the leading cause of death worldwide, with physical inactivity being a known contributor to the global rates of CVD incidence. CVD incidence, however, is not uniform with recognized sex differences as well and racial and ethnic differences. Furthermore, gut microbiota have been associated with CVD, sex, and race/ethnicity. Researchers have begun to examine the interplay of these complicated yet interrelated topics. This review will present evidence that CVD (risk and development), and gut microbiota are distinct between the sexes and racial/ethnic groups, which appear to be influenced by acculturation, discrimination, stress, and lifestyle factors like exercise. Furthermore, this review will address the beneficial impacts of exercise on the cardiovascular system and will provide recommendations for future research in the field.
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series Reviews in Cardiovascular Medicine
spelling doaj-art-afc20a3d1f42435cb80fbbfab497a8f12025-08-20T02:55:06ZengIMR PressReviews in Cardiovascular Medicine1530-65502025-02-012622643010.31083/RCM26430S1530-6550(24)01695-8Getting to the Heart of the Matter: Exploring the Intersection of Cardiovascular Disease, Sex and Race and How Exercise, and Gut Microbiota Influence these RelationshipsJohn J. Guers0Kevin S. Heffernan1Sara C. Campbell2Department of Health Sciences and Nursing, Rider University, Lawrenceville, NJ 08648, USADepartment of Biobehavioral Sciences, Teachers College, Columbia University, New York, NY 10027, USADepartment of Kinesiology and Health, The State University of New Jersey, New Brunswick, NJ 08901, USACardiovascular disease (CVD) is the leading cause of death worldwide, with physical inactivity being a known contributor to the global rates of CVD incidence. CVD incidence, however, is not uniform with recognized sex differences as well and racial and ethnic differences. Furthermore, gut microbiota have been associated with CVD, sex, and race/ethnicity. Researchers have begun to examine the interplay of these complicated yet interrelated topics. This review will present evidence that CVD (risk and development), and gut microbiota are distinct between the sexes and racial/ethnic groups, which appear to be influenced by acculturation, discrimination, stress, and lifestyle factors like exercise. Furthermore, this review will address the beneficial impacts of exercise on the cardiovascular system and will provide recommendations for future research in the field.https://www.imrpress.com/journal/RCM/26/2/10.31083/RCM26430cardiovascular diseaseethnicitymicrobiomeheartintestinephysical activity
spellingShingle John J. Guers
Kevin S. Heffernan
Sara C. Campbell
Getting to the Heart of the Matter: Exploring the Intersection of Cardiovascular Disease, Sex and Race and How Exercise, and Gut Microbiota Influence these Relationships
Reviews in Cardiovascular Medicine
cardiovascular disease
ethnicity
microbiome
heart
intestine
physical activity
title Getting to the Heart of the Matter: Exploring the Intersection of Cardiovascular Disease, Sex and Race and How Exercise, and Gut Microbiota Influence these Relationships
title_full Getting to the Heart of the Matter: Exploring the Intersection of Cardiovascular Disease, Sex and Race and How Exercise, and Gut Microbiota Influence these Relationships
title_fullStr Getting to the Heart of the Matter: Exploring the Intersection of Cardiovascular Disease, Sex and Race and How Exercise, and Gut Microbiota Influence these Relationships
title_full_unstemmed Getting to the Heart of the Matter: Exploring the Intersection of Cardiovascular Disease, Sex and Race and How Exercise, and Gut Microbiota Influence these Relationships
title_short Getting to the Heart of the Matter: Exploring the Intersection of Cardiovascular Disease, Sex and Race and How Exercise, and Gut Microbiota Influence these Relationships
title_sort getting to the heart of the matter exploring the intersection of cardiovascular disease sex and race and how exercise and gut microbiota influence these relationships
topic cardiovascular disease
ethnicity
microbiome
heart
intestine
physical activity
url https://www.imrpress.com/journal/RCM/26/2/10.31083/RCM26430
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