A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab
Secukinumab is an IgG monoclonal antibody widely used for treatment of ankylosing spondylitis, psoriasis, and psoriatic arthritis. Recently, there has been increasing controversy regarding potential adverse effects of the drug especially in those with underlying inflammatory bowel disease. We presen...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2019/2975631 |
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| _version_ | 1832551755573886976 |
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| author | Ted George Achufusi Prateek S. Harnee Sekou Rawlins |
| author_facet | Ted George Achufusi Prateek S. Harnee Sekou Rawlins |
| author_sort | Ted George Achufusi |
| collection | DOAJ |
| description | Secukinumab is an IgG monoclonal antibody widely used for treatment of ankylosing spondylitis, psoriasis, and psoriatic arthritis. Recently, there has been increasing controversy regarding potential adverse effects of the drug especially in those with underlying inflammatory bowel disease. We present the case of a young male patient who developed severe new-onset ulcerative colitis following initiation of secukinumab for psoriasis, with excellent response and rapid resolution of symptoms with infliximab. |
| format | Article |
| id | doaj-art-afb3884c1c284814a771db562f46c73c |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-afb3884c1c284814a771db562f46c73c2025-02-03T06:00:34ZengWileyCase Reports in Medicine1687-96271687-96352019-01-01201910.1155/2019/29756312975631A Rare Case of New-Onset Ulcerative Colitis following Initiation of SecukinumabTed George Achufusi0Prateek S. Harnee1Sekou Rawlins2Department of Internal Medicine, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USADepartment of Internal Medicine, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USADepartment of Gastroenterology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USASecukinumab is an IgG monoclonal antibody widely used for treatment of ankylosing spondylitis, psoriasis, and psoriatic arthritis. Recently, there has been increasing controversy regarding potential adverse effects of the drug especially in those with underlying inflammatory bowel disease. We present the case of a young male patient who developed severe new-onset ulcerative colitis following initiation of secukinumab for psoriasis, with excellent response and rapid resolution of symptoms with infliximab.http://dx.doi.org/10.1155/2019/2975631 |
| spellingShingle | Ted George Achufusi Prateek S. Harnee Sekou Rawlins A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab Case Reports in Medicine |
| title | A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab |
| title_full | A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab |
| title_fullStr | A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab |
| title_full_unstemmed | A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab |
| title_short | A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab |
| title_sort | rare case of new onset ulcerative colitis following initiation of secukinumab |
| url | http://dx.doi.org/10.1155/2019/2975631 |
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