A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab

Secukinumab is an IgG monoclonal antibody widely used for treatment of ankylosing spondylitis, psoriasis, and psoriatic arthritis. Recently, there has been increasing controversy regarding potential adverse effects of the drug especially in those with underlying inflammatory bowel disease. We presen...

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Bibliographic Details
Main Authors: Ted George Achufusi, Prateek S. Harnee, Sekou Rawlins
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2019/2975631
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Summary:Secukinumab is an IgG monoclonal antibody widely used for treatment of ankylosing spondylitis, psoriasis, and psoriatic arthritis. Recently, there has been increasing controversy regarding potential adverse effects of the drug especially in those with underlying inflammatory bowel disease. We present the case of a young male patient who developed severe new-onset ulcerative colitis following initiation of secukinumab for psoriasis, with excellent response and rapid resolution of symptoms with infliximab.
ISSN:1687-9627
1687-9635