Two-pore channels in MR1-dependent presentation of Mycobacterium tuberculosis infection.
MR1 is a ubiquitously expressed MHC-Ib molecule that presents microbial metabolites to MR1-restricted T cells, but there are differences in the antigen presentation pathway of an intracellular microbe compared to exogenously delivered antigen. We have shown the importance of endosomal trafficking pr...
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| Main Authors: | Elham Karamooz, Se-Jin Kim, Jessie C Peterson, Allison E Tammen, Shogo Soma, Aviva C R Soll, Erin W Meermeier, Sharon Khuzwayo, David M Lewinsohn |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-08-01
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| Series: | PLoS Pathogens |
| Online Access: | https://doi.org/10.1371/journal.ppat.1013342 |
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