Two-pore channels in MR1-dependent presentation of Mycobacterium tuberculosis infection.

MR1 is a ubiquitously expressed MHC-Ib molecule that presents microbial metabolites to MR1-restricted T cells, but there are differences in the antigen presentation pathway of an intracellular microbe compared to exogenously delivered antigen. We have shown the importance of endosomal trafficking pr...

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Bibliographic Details
Main Authors: Elham Karamooz, Se-Jin Kim, Jessie C Peterson, Allison E Tammen, Shogo Soma, Aviva C R Soll, Erin W Meermeier, Sharon Khuzwayo, David M Lewinsohn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1013342
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