Neutrophils promote the activation of monocytes via ROS to boost systemic antitumor immunity after cryo-thermal therapy

Neutrophils promote the activation of monocytes via ROS to boost systemic antitumor immunity after cryo-thermal therapy

BackgroundThe characteristics of the tumor immunosuppressive microenvironment represent a major challenge that limits the efficacy of immunotherapy. Our previous results suggested that cryo-thermal therapy, a tumor ablation system developed in our laboratory, promotes macrophage M1-type polarization...

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Bibliographic Details
Main Authors: Shicheng Wang, Zelu Zhang, Junjun Wang, Yue Lou, Yongxin Zhu, Jiaqi You, Ping Liu, Lisa X. Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
Subjects:
neutrophil
monocyte
ROS
cryo-thermal therapy
antitumor immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1445513/full
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