A Novel Hybrid Deep Learning Model Enhanced with Explainable AI for Brain Tumor Multi-Classification from MRI Images

The life span and quality of a patient are greatly diminished by a brain tumor, a type of cancer. For patients, early diagnosis and effective treatment are very significant in this respect. To assist medical professionals in this difficult and error-prone process and improve both the accuracy and in...

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Bibliographic Details
Main Author: Esra Gundogan
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Applied Sciences
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Online Access:https://www.mdpi.com/2076-3417/15/10/5412
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Summary:The life span and quality of a patient are greatly diminished by a brain tumor, a type of cancer. For patients, early diagnosis and effective treatment are very significant in this respect. To assist medical professionals in this difficult and error-prone process and improve both the accuracy and interpretability of the model, this study proposes a new hybrid deep learning model enhanced with explainable artificial intelligence for brain tumor multi-classification from MRI images. It integrates a customized CNN model for feature extraction from images and the optimized XGBoost method with high classification success. It also incorporates Grad-CAM, which makes the black-box structure of the model transparent and the decision-making process more understandable. The proposed model classified four different brain tumors, namely glioma, meningioma, notumor and pituitary, with 99.77% accuracy and demonstrated superior performance when compared with existing methods. The results show that a robust, interpretable and high-performance hybrid classification model has been developed for brain tumor detection.
ISSN:2076-3417