Insights on the role of TLR-4 in neuroinflammation: a hint on COVID-19 relationship

Insights on the role of TLR-4 in neuroinflammation: a hint on COVID-19 relationship

Neuroinflammation plays a crucial role in cognitive decline and neurodegenerative diseases, such as Alzheimer's. Within the central nervous system, microglia express Toll-like receptor 4 (TLR-4) abundantly, which prompts the secretion of proinflammatory cytokines like TNF-α, PGE2, IL-1β, and NO...

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Bibliographic Details
Main Authors: Salma A. Elshafey, Dalia El-Khouly, Esther T. Menze, Mariane G. Tadros
Format: Article
Language:English
Published: Ain Shams University 2023-12-01
Series:Archives of Pharmaceutical Sciences Ain Shams University
Subjects:
microglia
inflammation
toll-like receptor 4
myd88
nf-kb
sars-cov-2.
Online Access:https://aps.journals.ekb.eg/article_320652.html
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