Castleman Disease: An Unexpected Cause of a Solitary Pleural Mass

Castleman disease (CD) is a rare benign lymphoproliferative disorder, the etiology of which is unclear. Clinically it may manifest as localized disease (unicentric) or disseminated disease (multicentric). CD occurs in the thorax in 70% of cases, abdomen and pelvis in 15%, and in the neck in 10–15% o...

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Main Authors: Fiachra Moloney, Maria Twomey, John Hinchion, Michael Maher
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Radiology
Online Access:http://dx.doi.org/10.1155/2013/130515
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author Fiachra Moloney
Maria Twomey
John Hinchion
Michael Maher
author_facet Fiachra Moloney
Maria Twomey
John Hinchion
Michael Maher
author_sort Fiachra Moloney
collection DOAJ
description Castleman disease (CD) is a rare benign lymphoproliferative disorder, the etiology of which is unclear. Clinically it may manifest as localized disease (unicentric) or disseminated disease (multicentric). CD occurs in the thorax in 70% of cases, abdomen and pelvis in 15%, and in the neck in 10–15% of cases. We present a case of a pleural mass located posteriorly in a paraspinal location, which was discovered incidentally in a 50-year-old man and was subsequently resected followed by an unexpected diagnosis of Castleman disease on histological examination. In this report, we review the clinical and histological findings in a rare presentation of Castleman disease and discuss the findings in this case as part of an overall review of the typical radiological findings seen in Castleman disease.
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series Case Reports in Radiology
spelling doaj-art-af65c6f68e2248439171e294e46dac242025-02-03T06:07:27ZengWileyCase Reports in Radiology2090-68622090-68702013-01-01201310.1155/2013/130515130515Castleman Disease: An Unexpected Cause of a Solitary Pleural MassFiachra Moloney0Maria Twomey1John Hinchion2Michael Maher3Department of Radiology, Cork University Hospital, Wilton, Cork, IrelandDepartment of Radiology, Cork University Hospital, Wilton, Cork, IrelandDepartment of Cardiothoracic Surgery, Cork University Hospital, Wilton, Cork, IrelandDepartment of Radiology, Cork University Hospital, Wilton, Cork, IrelandCastleman disease (CD) is a rare benign lymphoproliferative disorder, the etiology of which is unclear. Clinically it may manifest as localized disease (unicentric) or disseminated disease (multicentric). CD occurs in the thorax in 70% of cases, abdomen and pelvis in 15%, and in the neck in 10–15% of cases. We present a case of a pleural mass located posteriorly in a paraspinal location, which was discovered incidentally in a 50-year-old man and was subsequently resected followed by an unexpected diagnosis of Castleman disease on histological examination. In this report, we review the clinical and histological findings in a rare presentation of Castleman disease and discuss the findings in this case as part of an overall review of the typical radiological findings seen in Castleman disease.http://dx.doi.org/10.1155/2013/130515
spellingShingle Fiachra Moloney
Maria Twomey
John Hinchion
Michael Maher
Castleman Disease: An Unexpected Cause of a Solitary Pleural Mass
Case Reports in Radiology
title Castleman Disease: An Unexpected Cause of a Solitary Pleural Mass
title_full Castleman Disease: An Unexpected Cause of a Solitary Pleural Mass
title_fullStr Castleman Disease: An Unexpected Cause of a Solitary Pleural Mass
title_full_unstemmed Castleman Disease: An Unexpected Cause of a Solitary Pleural Mass
title_short Castleman Disease: An Unexpected Cause of a Solitary Pleural Mass
title_sort castleman disease an unexpected cause of a solitary pleural mass
url http://dx.doi.org/10.1155/2013/130515
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AT mariatwomey castlemandiseaseanunexpectedcauseofasolitarypleuralmass
AT johnhinchion castlemandiseaseanunexpectedcauseofasolitarypleuralmass
AT michaelmaher castlemandiseaseanunexpectedcauseofasolitarypleuralmass