Long-Term Safety and Efficacy of Percutaneous Left Atrial Appendage Closure with the LAmbre Device
Background. Left atrial appendage closure (LAAC) using the LAmbre device has been associated with prevention of stroke in patients with nonvalvular atrial fibrillation (AF). Here, we interrogated the long-term safety and efficacy of using the LAmbre device in percutaneous LAAC. Methods. We analyzed...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Journal of Interventional Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2020/6613683 |
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| author | Guangji Wang Bin Kong Yu Liu He Huang |
| author_facet | Guangji Wang Bin Kong Yu Liu He Huang |
| author_sort | Guangji Wang |
| collection | DOAJ |
| description | Background. Left atrial appendage closure (LAAC) using the LAmbre device has been associated with prevention of stroke in patients with nonvalvular atrial fibrillation (AF). Here, we interrogated the long-term safety and efficacy of using the LAmbre device in percutaneous LAAC. Methods. We analyzed 56 records of patients with nonvalvular AF undergoing LAAC procedures with the LAmbre device. We collected and analyzed the data to define the safety and efficacy of the LAmbre device implantation. Result. The LAAC was successfully occluded in the 56 patients. Our data showed no serious residual leak or pericardial effusion occurred during the perioperative period. At a mean follow-up of 37.8 ± 23.5 months, there were 7.1%, 3.6%, and 3.6% rates of death, stroke, and device-related thrombus, respectively. There were no cases of severe residual leak or systemic embolism. Conclusion. Taken together, we demonstrate that execution of LAAC with the LAmbre device has high procedural success and prevents AF-related stroke. However, further large-scale trials might be required to confirm our findings. |
| format | Article |
| id | doaj-art-af5c4819541e4d4e953e99aaf9ba0580 |
| institution | Kabale University |
| issn | 0896-4327 1540-8183 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Interventional Cardiology |
| spelling | doaj-art-af5c4819541e4d4e953e99aaf9ba05802025-02-03T06:45:53ZengWileyJournal of Interventional Cardiology0896-43271540-81832020-01-01202010.1155/2020/66136836613683Long-Term Safety and Efficacy of Percutaneous Left Atrial Appendage Closure with the LAmbre DeviceGuangji Wang0Bin Kong1Yu Liu2He Huang3Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, Hubei, ChinaDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, Hubei, ChinaDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, Hubei, ChinaDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, Hubei, ChinaBackground. Left atrial appendage closure (LAAC) using the LAmbre device has been associated with prevention of stroke in patients with nonvalvular atrial fibrillation (AF). Here, we interrogated the long-term safety and efficacy of using the LAmbre device in percutaneous LAAC. Methods. We analyzed 56 records of patients with nonvalvular AF undergoing LAAC procedures with the LAmbre device. We collected and analyzed the data to define the safety and efficacy of the LAmbre device implantation. Result. The LAAC was successfully occluded in the 56 patients. Our data showed no serious residual leak or pericardial effusion occurred during the perioperative period. At a mean follow-up of 37.8 ± 23.5 months, there were 7.1%, 3.6%, and 3.6% rates of death, stroke, and device-related thrombus, respectively. There were no cases of severe residual leak or systemic embolism. Conclusion. Taken together, we demonstrate that execution of LAAC with the LAmbre device has high procedural success and prevents AF-related stroke. However, further large-scale trials might be required to confirm our findings.http://dx.doi.org/10.1155/2020/6613683 |
| spellingShingle | Guangji Wang Bin Kong Yu Liu He Huang Long-Term Safety and Efficacy of Percutaneous Left Atrial Appendage Closure with the LAmbre Device Journal of Interventional Cardiology |
| title | Long-Term Safety and Efficacy of Percutaneous Left Atrial Appendage Closure with the LAmbre Device |
| title_full | Long-Term Safety and Efficacy of Percutaneous Left Atrial Appendage Closure with the LAmbre Device |
| title_fullStr | Long-Term Safety and Efficacy of Percutaneous Left Atrial Appendage Closure with the LAmbre Device |
| title_full_unstemmed | Long-Term Safety and Efficacy of Percutaneous Left Atrial Appendage Closure with the LAmbre Device |
| title_short | Long-Term Safety and Efficacy of Percutaneous Left Atrial Appendage Closure with the LAmbre Device |
| title_sort | long term safety and efficacy of percutaneous left atrial appendage closure with the lambre device |
| url | http://dx.doi.org/10.1155/2020/6613683 |
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