Cupric Doping Hollow Prussian Blue Nanoplatform for Enhanced Cholesterol Depletion: a Promising Strategy for Breast Cancer Therapy and Metastasis Inhibition

Cupric Doping Hollow Prussian Blue Nanoplatform for Enhanced Cholesterol Depletion: a Promising Strategy for Breast Cancer Therapy and Metastasis Inhibition

Abstract The dysregulated cholesterol metabolism in breast cancer cells drives malignancy, invasion, and metastasis, emphasizing the significance of reducing abnormal cholesterol accumulation for effective cancer treatment and metastasis inhibition. Despite its promise, cholesterol oxidase (ChOx) en...

Full description

Saved in:

Bibliographic Details
Main Authors:	Shuangqian Yan, Panpan Xue, Ying Sun, Tingjie Bai, Sijie Shao, Xuemei Zeng
Format:	Article
Language:	English
Published:	Wiley 2025-01-01
Series:	Advanced Science
Subjects:	cholesterol metabolism regulation cholesterol oxidase metal organic frameworks tumor metabolism therapy tumor metastasis inhibition
Online Access:	https://doi.org/10.1002/advs.202409967
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

HDL-free cholesterol influx into macrophages and transfer to LDL correlate with HDL-free cholesterol content
by: Dedipya Yelamanchili, et al.
Published: (2025-01-01)

Dual Inhibition of CDK4/6 and CDK7 Suppresses Triple‐Negative Breast Cancer Progression via Epigenetic Modulation of SREBP1‐Regulated Cholesterol Metabolism
by: Yilan Yang, et al.
Published: (2025-02-01)

New epigenome players in the regulation of PCSK9-H3K4me3 and H3K9ac alterations by statin in hypercholesterolemia
by: Sushmitha Duddu, et al.
Published: (2025-01-01)

Role of high-density lipoprotein cholesterol in health and diseases
by: Brijesh Yadav, et al.
Published: (2021-01-01)

Optimized extraction and kinetic study of cholesterol oxidase from a newly isolated Escherichia fergusonii strain from local whey samples: insights through a combined experimental study and artificial neural network modeling
by: Simin Khataee, et al.
Published: (2025-01-01)

The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet
by: Deniz Uluışık, et al.

Lipid metabolic reprogramming and associated ferroptosis in osteosarcoma: From molecular mechanisms to potential targets
by: Zhiyang Yin, et al.
Published: (2025-04-01)

Biological Functions and Clinical Significance of the ABCG1 Transporter
by: Stanislav Kotlyarov, et al.
Published: (2024-12-01)

Bisphenol A attenuates testosterone synthesis via increasing apolipoprotein A1-mediated reverse cholesterol transport in mice
by: Tong Zhao, et al.
Published: (2025-01-01)

Beyond LDL cholesterol: remnant cholesterol is associated with cardiometabolic risk factors in children
by: Ana Torres-Costoso, et al.
Published: (2025-01-01)

The relationship between cholesterol levels and thyroid eye disease
by: Caroline Cardo, et al.
Published: (2025-02-01)

Perspective: Current Scientific Evidence and Research Strategies in the Role of Almonds in Cardiometabolic Health
by: Paula R Trumbo, et al.
Published: (2025-01-01)

The levels of the blood serum thyroid hormones, glucose and cholesterol in swiss brown cows which were at the lactation
by: Tufan Keçeci, et al.

Association between non-high-density lipoprotein cholesterol-to-high-density lipoprotein cholesterol ratio and macroalbuminuria: evidence from NHANES 1999-2018
by: Dongli Huang, et al.
Published: (2025-02-01)

Association between the neutrophil-to-high-density lipoprotein cholesterol ratio with kidney stone risk: a cross-sectional study
by: Yuan-Zhuo Du, et al.
Published: (2025-02-01)

Association between remnant cholesterol and depression in middle-aged and older Chinese adults: a population-based cohort study
by: Yang Zhou, et al.
Published: (2025-02-01)

The role of cholesterol in modifying the lipid-lowering effects of Fuzhuan brick-tea in Caenorhabditis elegans via SBP-1/SREBP
by: Lianyun Pan, et al.
Published: (2023-11-01)

The Impact of Astaxanthin Supplementation on the Lipid Profile
by: Filip Arczewski, et al.
Published: (2025-02-01)

Dynamics of HDL-Cholesterol Following a Post-Myocardial Infarction Cardiac Rehabilitation Program
by: Carlos Bertolín-Boronat, et al.
Published: (2025-01-01)

FDFT1 inhibits macrophage M1 polarization and promotes colorectal cancer progression
by: GAO Yuan, et al.
Published: (2025-02-01)

The role of lipids and lipids lowering drugs in human papillomavirus (HPV) and HPV-associated cancers
by: Ehsan Shabani, et al.
Published: (2025-01-01)

Development and application of an LC-MS/MS method for the combined quantification of oxysterols and bile acids
by: Martin Roumain, et al.
Published: (2025-01-01)

HUBUNGAN KADAR KOLESTEROL DENGAN TEKANAN DARAH PENDERITA HIPERTENSI DI DUSUN SIDOMULYO DESA REJOAGUNG KECAMATAN PLOSO KABUPATEN JOMBANG The Correlation of Cholesterol levels with Blood Pressure Hypertension Patients in Sidomulyo Rejoagung Village Distric
by: HENI MARYATI
Published: (2017-07-01)

Recent trends in research on the role of cholesterol in leukemia: a bibliometric and visualization study
by: Huijuan Lv, et al.
Published: (2025-01-01)

The effect of green tea consumption on cholesterol reduction: a study among social service employees in East Nusa Tenggara
by: Patricia Flamli Uma Mukin, et al.
Published: (2024-12-01)

Evaluating chia (Salvia hispanica L.) seed administration for cholesterol reduction in quail (Coturnix coturnix)
by: Rahimatul Uthia, et al.
Published: (2024-12-01)

National Health Laboratory Service (NHLS) changes the method of LDL-cholesterol calculation in South Africa
by: T Pillay, et al.
Published: (2023-12-01)

Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD
by: Shaowei Wang, et al.
Published: (2025-02-01)

Targeting lipid metabolism of macrophages: A new strategy for tumor therapy
by: Nan Shao, et al.
Published: (2025-02-01)

Serum HDL and their subfractions are impaired in multisystem inflammatory syndrome in children (MIS-C)
by: Antonietta Giannattasio, et al.
Published: (2025-01-01)

Blood Lipid Levels and Their Value as Markers of Disease Activity in Severe Ulcerative Colitis
by: Zhu L, et al.
Published: (2025-02-01)

TGF-β induces cholesterol accumulation to regulate the secretion of tumor-derived extracellular vesicles
by: Dorival Mendes Rodrigues-Junior, et al.
Published: (2025-02-01)

Cholesterol Targeted Catalytic Hydrogel Fueled by Tumor Debris can Enhance Microwave Ablation Therapy and Anti‐Tumor Immune Response
by: Lin Shen, et al.
Published: (2025-02-01)

Inhibitory effect of procyanidin B2 and tannin acid on cholesterol esterase and their synergistic effect with orlistat
by: Xiangxin Li, et al.
Published: (2024-01-01)

Elucidating the role of pyrimidine metabolism in prostate cancer and its therapeutic implications
by: Liang Huang, et al.
Published: (2025-01-01)

Hypothesis on the role of cholesterol crystals in spontaneously ruptured aortic plaques: Potential triggers for inflammation and systemic effects
by: Chikao Yutani, et al.
Published: (2025-03-01)

The association between neutrophil to high-density lipoprotein cholesterol ratio and gallstones: a cross-sectional study
by: Yinkang Wang, et al.
Published: (2025-01-01)

Correlation between gallstones and fasting blood glucose to serum high-density lipoprotein cholesterol ratio among American adults
by: Bo Wu, et al.
Published: (2025-01-01)

Relationship of serum total cholesterol and triglyceride with risk of mortality in maintenance hemodialysis patients: a multicenter prospective cohort study
by: Yan Huang, et al.
Published: (2024-12-01)

Association of albumin to non-high-density lipoprotein cholesterol ratio with mortality in peritoneal dialysis patients
by: Yongjie Xie, et al.
Published: (2024-12-01)