Relation between pulmonary function changes and diaphragmatic ultrasound in patients with idiopathic pulmonary fibrosis

Abstract Background IPF is a chronic disease with impaired diaphragmatic function. In the vast majority of patients, lung function gradually deteriorates until intractable respiratory failure occurs. Aim of work To assess diaphragmatic ultrasound in IPF patients and its relation to functional parame...

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Main Authors: Alaa Ahmed Ibrahim, Aya Mohamed Mohamed Abd-Eldayem, Hossam Eldin Mohamed Abdel Hamid
Format: Article
Language:English
Published: SpringerOpen 2025-01-01
Series:The Egyptian Journal of Bronchology
Subjects:
Online Access:https://doi.org/10.1186/s43168-025-00365-7
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author Alaa Ahmed Ibrahim
Aya Mohamed Mohamed Abd-Eldayem
Hossam Eldin Mohamed Abdel Hamid
author_facet Alaa Ahmed Ibrahim
Aya Mohamed Mohamed Abd-Eldayem
Hossam Eldin Mohamed Abdel Hamid
author_sort Alaa Ahmed Ibrahim
collection DOAJ
description Abstract Background IPF is a chronic disease with impaired diaphragmatic function. In the vast majority of patients, lung function gradually deteriorates until intractable respiratory failure occurs. Aim of work To assess diaphragmatic ultrasound in IPF patients and its relation to functional parameters. Subjects and methods This study used a case–control design and involved IPF patients who were either attending an outpatient clinic or admitted to a ward at Ain Shams University Hospitals and Abbassia Chest Hospital. Forty-five participants were included and split up into 3 groups: group A: 15 IPF cases suffering from hypoxia. Group B: 15 IPF patients without hypoxia or respiratory failure. Group C: 15 healthy participants as controls. Result Groups A and B had considerably decreased diaphragm excursion (QB), thickness of diaphragm at the end of inspiration, diaphragm thickness fraction, and diaphragm thickness fraction % when compared to the control group. Patients' diaphragm excursion during deep breathing was significantly smaller in group A than it was in the controls. The diaphragm excursion (QB and DB), the thickness of the diaphragm at the end of inspiration, the thickness fraction, and the fraction % were positively associated with FVC, FEF 25–75, FEV1, 6MWT, the O2 sat before, the O2 sat after, and the O2 at RA, while they were negatively correlated with FEV1/FVC. There was no difference between groups in diaphragm thickness at the end of expiration. Conclusion Diaphragmatic ultrasound parameters demonstrated strong correlations with pulmonary function parameters, 6-min walk test, and oxygen saturation levels.
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spelling doaj-art-af4037e24ff34b819f2b1dbaccc8ebc42025-01-19T12:13:06ZengSpringerOpenThe Egyptian Journal of Bronchology2314-85512025-01-0119111110.1186/s43168-025-00365-7Relation between pulmonary function changes and diaphragmatic ultrasound in patients with idiopathic pulmonary fibrosisAlaa Ahmed Ibrahim0Aya Mohamed Mohamed Abd-Eldayem1Hossam Eldin Mohamed Abdel Hamid2Ain Shams UniversityAin Shams UniversityAin Shams UniversityAbstract Background IPF is a chronic disease with impaired diaphragmatic function. In the vast majority of patients, lung function gradually deteriorates until intractable respiratory failure occurs. Aim of work To assess diaphragmatic ultrasound in IPF patients and its relation to functional parameters. Subjects and methods This study used a case–control design and involved IPF patients who were either attending an outpatient clinic or admitted to a ward at Ain Shams University Hospitals and Abbassia Chest Hospital. Forty-five participants were included and split up into 3 groups: group A: 15 IPF cases suffering from hypoxia. Group B: 15 IPF patients without hypoxia or respiratory failure. Group C: 15 healthy participants as controls. Result Groups A and B had considerably decreased diaphragm excursion (QB), thickness of diaphragm at the end of inspiration, diaphragm thickness fraction, and diaphragm thickness fraction % when compared to the control group. Patients' diaphragm excursion during deep breathing was significantly smaller in group A than it was in the controls. The diaphragm excursion (QB and DB), the thickness of the diaphragm at the end of inspiration, the thickness fraction, and the fraction % were positively associated with FVC, FEF 25–75, FEV1, 6MWT, the O2 sat before, the O2 sat after, and the O2 at RA, while they were negatively correlated with FEV1/FVC. There was no difference between groups in diaphragm thickness at the end of expiration. Conclusion Diaphragmatic ultrasound parameters demonstrated strong correlations with pulmonary function parameters, 6-min walk test, and oxygen saturation levels.https://doi.org/10.1186/s43168-025-00365-7Diaphragmatic ultrasoundIPFThickness fractionPulmonary functions
spellingShingle Alaa Ahmed Ibrahim
Aya Mohamed Mohamed Abd-Eldayem
Hossam Eldin Mohamed Abdel Hamid
Relation between pulmonary function changes and diaphragmatic ultrasound in patients with idiopathic pulmonary fibrosis
The Egyptian Journal of Bronchology
Diaphragmatic ultrasound
IPF
Thickness fraction
Pulmonary functions
title Relation between pulmonary function changes and diaphragmatic ultrasound in patients with idiopathic pulmonary fibrosis
title_full Relation between pulmonary function changes and diaphragmatic ultrasound in patients with idiopathic pulmonary fibrosis
title_fullStr Relation between pulmonary function changes and diaphragmatic ultrasound in patients with idiopathic pulmonary fibrosis
title_full_unstemmed Relation between pulmonary function changes and diaphragmatic ultrasound in patients with idiopathic pulmonary fibrosis
title_short Relation between pulmonary function changes and diaphragmatic ultrasound in patients with idiopathic pulmonary fibrosis
title_sort relation between pulmonary function changes and diaphragmatic ultrasound in patients with idiopathic pulmonary fibrosis
topic Diaphragmatic ultrasound
IPF
Thickness fraction
Pulmonary functions
url https://doi.org/10.1186/s43168-025-00365-7
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AT ayamohamedmohamedabdeldayem relationbetweenpulmonaryfunctionchangesanddiaphragmaticultrasoundinpatientswithidiopathicpulmonaryfibrosis
AT hossameldinmohamedabdelhamid relationbetweenpulmonaryfunctionchangesanddiaphragmaticultrasoundinpatientswithidiopathicpulmonaryfibrosis