Clinico-epidemiology and aetiopathogenesis of gallstone disease in the South Asian region: a scoping review protocol

Introduction Pathogenesis of gallstones (GS) is multifactorial and is influenced by numerous environmental and genetic risk factors. As a result, clinico-epidemiology and aetiopathogenesis of GS vary in different populations. Understanding the aetiopathogenesis of GS for different populations is imp...

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Main Authors: Harshi Weerakoon, Ishari Vithanage, Oshadhi Alahakoon, Kosala Weerakoon
Format: Article
Language:English
Published: BMJ Publishing Group 2022-06-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/6/e057808.full
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author Harshi Weerakoon
Ishari Vithanage
Oshadhi Alahakoon
Kosala Weerakoon
author_facet Harshi Weerakoon
Ishari Vithanage
Oshadhi Alahakoon
Kosala Weerakoon
author_sort Harshi Weerakoon
collection DOAJ
description Introduction Pathogenesis of gallstones (GS) is multifactorial and is influenced by numerous environmental and genetic risk factors. As a result, clinico-epidemiology and aetiopathogenesis of GS vary in different populations. Understanding the aetiopathogenesis of GS for different populations is imperative in control and prevention of GS disease and its associated complications. This protocol describes the methodology of a scoping review which focuses on synthesising the most updated knowledge on GS disease in South Asia.Methods and analysis The scoping review proposed in this protocol will be guided by Arksey and O’Malley’s framework and the Joanna Briggs Institute Reviewers’ Manual. Accordingly, population, concept and context strategy will be used to formulate the scoping review question, eligibility criteria and search strategy. In the search, electronic databases, MEDLINE/PubMed, ScienceDirect, Scopus, Cochrane library, CINAHL, Trip, and Google scholar, as well as various grey literature sources will be used in synthesising and presenting the findings on clinico-epidemiology and aetiopathogenesis of GS disease in South Asia.Ethics and dissemination As secondary data will be used in the study, ethical approval will not be required. The scoping review proposed by this protocol will accurately summarise the current knowledge on GS disease in South Asia based on published and unpublished literature on the field. Thus, the evidence presented in the review will be important for healthcare providers to make decisions on the control and prevention of GS disease and as well as to identify future research priorities on GS disease in South Asia.
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spelling doaj-art-af3b37fdd1a54adfa1b20d8d5e2b89cc2025-01-27T12:10:09ZengBMJ Publishing GroupBMJ Open2044-60552022-06-0112610.1136/bmjopen-2021-057808Clinico-epidemiology and aetiopathogenesis of gallstone disease in the South Asian region: a scoping review protocolHarshi Weerakoon0Ishari Vithanage1Oshadhi Alahakoon2Kosala Weerakoon3Department of Biochemistry, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri LankaDepartment of Biochemistry, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri LankaDepartment of Biochemistry, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri LankaDepartment of Parasitology, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri LankaIntroduction Pathogenesis of gallstones (GS) is multifactorial and is influenced by numerous environmental and genetic risk factors. As a result, clinico-epidemiology and aetiopathogenesis of GS vary in different populations. Understanding the aetiopathogenesis of GS for different populations is imperative in control and prevention of GS disease and its associated complications. This protocol describes the methodology of a scoping review which focuses on synthesising the most updated knowledge on GS disease in South Asia.Methods and analysis The scoping review proposed in this protocol will be guided by Arksey and O’Malley’s framework and the Joanna Briggs Institute Reviewers’ Manual. Accordingly, population, concept and context strategy will be used to formulate the scoping review question, eligibility criteria and search strategy. In the search, electronic databases, MEDLINE/PubMed, ScienceDirect, Scopus, Cochrane library, CINAHL, Trip, and Google scholar, as well as various grey literature sources will be used in synthesising and presenting the findings on clinico-epidemiology and aetiopathogenesis of GS disease in South Asia.Ethics and dissemination As secondary data will be used in the study, ethical approval will not be required. The scoping review proposed by this protocol will accurately summarise the current knowledge on GS disease in South Asia based on published and unpublished literature on the field. Thus, the evidence presented in the review will be important for healthcare providers to make decisions on the control and prevention of GS disease and as well as to identify future research priorities on GS disease in South Asia.https://bmjopen.bmj.com/content/12/6/e057808.full
spellingShingle Harshi Weerakoon
Ishari Vithanage
Oshadhi Alahakoon
Kosala Weerakoon
Clinico-epidemiology and aetiopathogenesis of gallstone disease in the South Asian region: a scoping review protocol
BMJ Open
title Clinico-epidemiology and aetiopathogenesis of gallstone disease in the South Asian region: a scoping review protocol
title_full Clinico-epidemiology and aetiopathogenesis of gallstone disease in the South Asian region: a scoping review protocol
title_fullStr Clinico-epidemiology and aetiopathogenesis of gallstone disease in the South Asian region: a scoping review protocol
title_full_unstemmed Clinico-epidemiology and aetiopathogenesis of gallstone disease in the South Asian region: a scoping review protocol
title_short Clinico-epidemiology and aetiopathogenesis of gallstone disease in the South Asian region: a scoping review protocol
title_sort clinico epidemiology and aetiopathogenesis of gallstone disease in the south asian region a scoping review protocol
url https://bmjopen.bmj.com/content/12/6/e057808.full
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