Evaluating genome-wide association study-identified breast cancer risk variants in African-American women.

Evaluating genome-wide association study-identified breast cancer risk variants in African-American women.

Genome-wide association studies (GWAS), conducted mostly in European or Asian descendants, have identified approximately 67 genetic susceptibility loci for breast cancer. Given the large differences in genetic architecture between the African-ancestry genome and genomes of Asians and Europeans, it i...

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Main Authors: Jirong Long, Ben Zhang, Lisa B Signorello, Qiuyin Cai, Sandra Deming-Halverson, Martha J Shrubsole, Maureen Sanderson, Joe Dennis, Kyriaki Michailidou, Douglas F Easton, Xiao-Ou Shu, William J Blot, Wei Zheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0058350&type=printable
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