Carbimazole Induced Pleural Effusion: A Case Report

Objective. To describe a patient with unilateral exudative pleural effusion that developed after commencement of carbimazole. Methods. We describe the presentation and clinical journey of an elderly woman who presented to the chest physicians initially with pleural effusion but was followed up by th...

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Main Authors: Gautam Das, Stephen E. R. S. Stanaway, Liz Brohan
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2012/941241
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author Gautam Das
Stephen E. R. S. Stanaway
Liz Brohan
author_facet Gautam Das
Stephen E. R. S. Stanaway
Liz Brohan
author_sort Gautam Das
collection DOAJ
description Objective. To describe a patient with unilateral exudative pleural effusion that developed after commencement of carbimazole. Methods. We describe the presentation and clinical journey of an elderly woman who presented to the chest physicians initially with pleural effusion but was followed up by the endocrinology team. Result. The patient was a 77-year-old Caucasian woman who presented with symptoms of breathlessness and a confirmed unilateral pleural effusion while being on treatment for thyrotoxicosis. Her symptoms needed recurrent hospital admission for investigations and drainage, but no potential cause was identified after extensive investigations. A drug-induced exudative effusion consequent to carbimazole intake was diagnosed as discontinuation of the drug lead to complete resolution of the effusion with no recurrence. Conclusion. Physicians and Endocrinologist must bear in mind that this potentially rare complication of carbimazole while treating patients of thyrotoxicosis as appearance of similar features in their patients while being on carbimazole should lead to the discontinuation of the drug, and alternative treatment strategy should be considered.
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spelling doaj-art-aefe2fbcf84b412fb81de6a8ea0bcbba2025-08-20T02:23:15ZengWileyCase Reports in Endocrinology2090-65012090-651X2012-01-01201210.1155/2012/941241941241Carbimazole Induced Pleural Effusion: A Case ReportGautam Das0Stephen E. R. S. Stanaway1Liz Brohan2Department of Diabetes and Endocrinology, Glan Clwyd Hospital, Rhuddlan Road, Bodelwyddan, Rhyl LL18 5UJ, UKDepartment of Diabetes and Endocrinology, Wrexham Maelor Hospital, Croesnewyyd Road, Wrexham LL13 7TD, UKDepartment of Respiratory Medicine, Wrexham Maelor Hospital, Croesnewyyd Road, Wrexham LL13 7TD, UKObjective. To describe a patient with unilateral exudative pleural effusion that developed after commencement of carbimazole. Methods. We describe the presentation and clinical journey of an elderly woman who presented to the chest physicians initially with pleural effusion but was followed up by the endocrinology team. Result. The patient was a 77-year-old Caucasian woman who presented with symptoms of breathlessness and a confirmed unilateral pleural effusion while being on treatment for thyrotoxicosis. Her symptoms needed recurrent hospital admission for investigations and drainage, but no potential cause was identified after extensive investigations. A drug-induced exudative effusion consequent to carbimazole intake was diagnosed as discontinuation of the drug lead to complete resolution of the effusion with no recurrence. Conclusion. Physicians and Endocrinologist must bear in mind that this potentially rare complication of carbimazole while treating patients of thyrotoxicosis as appearance of similar features in their patients while being on carbimazole should lead to the discontinuation of the drug, and alternative treatment strategy should be considered.http://dx.doi.org/10.1155/2012/941241
spellingShingle Gautam Das
Stephen E. R. S. Stanaway
Liz Brohan
Carbimazole Induced Pleural Effusion: A Case Report
Case Reports in Endocrinology
title Carbimazole Induced Pleural Effusion: A Case Report
title_full Carbimazole Induced Pleural Effusion: A Case Report
title_fullStr Carbimazole Induced Pleural Effusion: A Case Report
title_full_unstemmed Carbimazole Induced Pleural Effusion: A Case Report
title_short Carbimazole Induced Pleural Effusion: A Case Report
title_sort carbimazole induced pleural effusion a case report
url http://dx.doi.org/10.1155/2012/941241
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