Gastric Undifferentiated Pleomorphic Sarcoma Presenting as a Rapidly Growing Subepithelial Tumor
A 48-year-old man presented to our hospital for evaluation of melena. Abdominal computed tomography (CT) revealed an endophytic contrast-enhanced mass (approximately 9 cm) in the gastric fundus and upper body. CT showed no evidence of metastasis to other organs. Endoscopic examination revealed a lar...
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Korean College of Helicobacter and Upper Gastrointestinal Research
2024-09-01
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| Series: | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
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| Online Access: | http://helicojournal.org/upload/pdf/kjhugr-2024-0033.pdf |
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| author | Dae Gon Ryu Cheol Woong Choi |
| author_facet | Dae Gon Ryu Cheol Woong Choi |
| author_sort | Dae Gon Ryu |
| collection | DOAJ |
| description | A 48-year-old man presented to our hospital for evaluation of melena. Abdominal computed tomography (CT) revealed an endophytic contrast-enhanced mass (approximately 9 cm) in the gastric fundus and upper body. CT showed no evidence of metastasis to other organs. Endoscopic examination revealed a large mass accompanied by an exudate and signs of surface hemorrhage. The shape of the mass resembled that of a subepithelial tumor, and >50% of the mucosa was peeled off. Endoscopic ultrasonography revealed hyperechoic spreading and dotor rod-shaped anechoic lesions arranged within an overall hypoechoic mass. The patient underwent total gastrectomy with lymph node dissection and was diagnosed with undifferentiated pleomorphic sarcoma without lymph node metastasis. Undifferentiated pleomorphic sarcoma, a high-grade aggressive soft tissue sarcoma, predominantly involves the extremities and rarely the stomach. It is usually asymptomatic but tends to grow rapidly. Endoscopic imaging performed a year prior to presentation was unremarkable. We report a case of a gastric undifferentiated pleomorphic sarcoma that presented as a rapidly growing subepithelial tumor. Malignancies other than a gastrointestinal stromal tumor should be considered in the differential diagnosis in patients presenting with a rapidly growing gastric subepithelial tumor. |
| format | Article |
| id | doaj-art-aef14e214b51470b886e3c9d2df8a60d |
| institution | DOAJ |
| issn | 1738-3331 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Korean College of Helicobacter and Upper Gastrointestinal Research |
| record_format | Article |
| series | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
| spelling | doaj-art-aef14e214b51470b886e3c9d2df8a60d2025-08-20T03:20:27ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312024-09-0124327628010.7704/kjhugr.2024.0033859Gastric Undifferentiated Pleomorphic Sarcoma Presenting as a Rapidly Growing Subepithelial TumorDae Gon Ryu0Cheol Woong Choi1Department of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, KoreaA 48-year-old man presented to our hospital for evaluation of melena. Abdominal computed tomography (CT) revealed an endophytic contrast-enhanced mass (approximately 9 cm) in the gastric fundus and upper body. CT showed no evidence of metastasis to other organs. Endoscopic examination revealed a large mass accompanied by an exudate and signs of surface hemorrhage. The shape of the mass resembled that of a subepithelial tumor, and >50% of the mucosa was peeled off. Endoscopic ultrasonography revealed hyperechoic spreading and dotor rod-shaped anechoic lesions arranged within an overall hypoechoic mass. The patient underwent total gastrectomy with lymph node dissection and was diagnosed with undifferentiated pleomorphic sarcoma without lymph node metastasis. Undifferentiated pleomorphic sarcoma, a high-grade aggressive soft tissue sarcoma, predominantly involves the extremities and rarely the stomach. It is usually asymptomatic but tends to grow rapidly. Endoscopic imaging performed a year prior to presentation was unremarkable. We report a case of a gastric undifferentiated pleomorphic sarcoma that presented as a rapidly growing subepithelial tumor. Malignancies other than a gastrointestinal stromal tumor should be considered in the differential diagnosis in patients presenting with a rapidly growing gastric subepithelial tumor.http://helicojournal.org/upload/pdf/kjhugr-2024-0033.pdfstomachneoplasmsarcoma |
| spellingShingle | Dae Gon Ryu Cheol Woong Choi Gastric Undifferentiated Pleomorphic Sarcoma Presenting as a Rapidly Growing Subepithelial Tumor The Korean Journal of Helicobacter and Upper Gastrointestinal Research stomach neoplasm sarcoma |
| title | Gastric Undifferentiated Pleomorphic Sarcoma Presenting as a Rapidly Growing Subepithelial Tumor |
| title_full | Gastric Undifferentiated Pleomorphic Sarcoma Presenting as a Rapidly Growing Subepithelial Tumor |
| title_fullStr | Gastric Undifferentiated Pleomorphic Sarcoma Presenting as a Rapidly Growing Subepithelial Tumor |
| title_full_unstemmed | Gastric Undifferentiated Pleomorphic Sarcoma Presenting as a Rapidly Growing Subepithelial Tumor |
| title_short | Gastric Undifferentiated Pleomorphic Sarcoma Presenting as a Rapidly Growing Subepithelial Tumor |
| title_sort | gastric undifferentiated pleomorphic sarcoma presenting as a rapidly growing subepithelial tumor |
| topic | stomach neoplasm sarcoma |
| url | http://helicojournal.org/upload/pdf/kjhugr-2024-0033.pdf |
| work_keys_str_mv | AT daegonryu gastricundifferentiatedpleomorphicsarcomapresentingasarapidlygrowingsubepithelialtumor AT cheolwoongchoi gastricundifferentiatedpleomorphicsarcomapresentingasarapidlygrowingsubepithelialtumor |