Degradation of Toxic Dye Using Phytomediated Copper Nanoparticles and Its Free-Radical Scavenging Potential and Antimicrobial Activity against Environmental Pathogens
The present investigation deals with the green synthesis of copper nanoparticles in an ecofriendly manner using leaf extract of Andrographis paniculata. Green-synthesized copper nanoparticles were studied for their antibacterial, antioxidant, and catalytic activity. The leaves were powdered and extr...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Bioinorganic Chemistry and Applications |
| Online Access: | http://dx.doi.org/10.1155/2021/1222908 |
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| author | S. Rajeshkumar M. Vanaja Arunachalam Kalirajan |
| author_facet | S. Rajeshkumar M. Vanaja Arunachalam Kalirajan |
| author_sort | S. Rajeshkumar |
| collection | DOAJ |
| description | The present investigation deals with the green synthesis of copper nanoparticles in an ecofriendly manner using leaf extract of Andrographis paniculata. Green-synthesized copper nanoparticles were studied for their antibacterial, antioxidant, and catalytic activity. The leaves were powdered and extracted with water and added to copper sulphate solution. The reduction of copper ions to nanoparticles was preliminarily identified by the color change of the reaction mixture. The synthesized nanoparticle was characterized by using a UV-Vis Spectrophotometer at a different wavelength with different time intervals. Functional groups available on the surface of the nanoparticle were identified by Fourier transform infrared spectroscopy (FTIR). Surface roughness was characterized by atomic force microscopy (AFM). X-ray diffraction (XRD) analysis showed six distinct intense peaks indicating the crystalline nature of synthesized copper nanoparticles (CuNPs). A scanning electron microscope (SEM) demonstrated polydispersed nanoparticles formed in the reaction process. The antibacterial activity of the nanoparticles was evaluated by an agar well diffusion assay against pathogenic bacteria. The antioxidant activity showed the excellent reduction of DPPH free radicals by nanoparticles. These results confirmed that copper nanoparticles serve as an alternative therapeutic agent over conventional drugs. Moreover, copper nanoparticles were also used to study the effect on the dye degradation process of methyl red and eosin dyes. Copper nanoparticles effectively remove the dyes with high efficiency up to 92% and 95% of methyl red and eosin dye, respectively. |
| format | Article |
| id | doaj-art-aee0469481df4ae59e9cead8d4dc768a |
| institution | Kabale University |
| issn | 1687-479X |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Bioinorganic Chemistry and Applications |
| spelling | doaj-art-aee0469481df4ae59e9cead8d4dc768a2025-02-03T01:21:04ZengWileyBioinorganic Chemistry and Applications1687-479X2021-01-01202110.1155/2021/1222908Degradation of Toxic Dye Using Phytomediated Copper Nanoparticles and Its Free-Radical Scavenging Potential and Antimicrobial Activity against Environmental PathogensS. Rajeshkumar0M. Vanaja1Arunachalam Kalirajan2Nanobiomedicine LabSPKCESDepartment of Science and MathematicsThe present investigation deals with the green synthesis of copper nanoparticles in an ecofriendly manner using leaf extract of Andrographis paniculata. Green-synthesized copper nanoparticles were studied for their antibacterial, antioxidant, and catalytic activity. The leaves were powdered and extracted with water and added to copper sulphate solution. The reduction of copper ions to nanoparticles was preliminarily identified by the color change of the reaction mixture. The synthesized nanoparticle was characterized by using a UV-Vis Spectrophotometer at a different wavelength with different time intervals. Functional groups available on the surface of the nanoparticle were identified by Fourier transform infrared spectroscopy (FTIR). Surface roughness was characterized by atomic force microscopy (AFM). X-ray diffraction (XRD) analysis showed six distinct intense peaks indicating the crystalline nature of synthesized copper nanoparticles (CuNPs). A scanning electron microscope (SEM) demonstrated polydispersed nanoparticles formed in the reaction process. The antibacterial activity of the nanoparticles was evaluated by an agar well diffusion assay against pathogenic bacteria. The antioxidant activity showed the excellent reduction of DPPH free radicals by nanoparticles. These results confirmed that copper nanoparticles serve as an alternative therapeutic agent over conventional drugs. Moreover, copper nanoparticles were also used to study the effect on the dye degradation process of methyl red and eosin dyes. Copper nanoparticles effectively remove the dyes with high efficiency up to 92% and 95% of methyl red and eosin dye, respectively.http://dx.doi.org/10.1155/2021/1222908 |
| spellingShingle | S. Rajeshkumar M. Vanaja Arunachalam Kalirajan Degradation of Toxic Dye Using Phytomediated Copper Nanoparticles and Its Free-Radical Scavenging Potential and Antimicrobial Activity against Environmental Pathogens Bioinorganic Chemistry and Applications |
| title | Degradation of Toxic Dye Using Phytomediated Copper Nanoparticles and Its Free-Radical Scavenging Potential and Antimicrobial Activity against Environmental Pathogens |
| title_full | Degradation of Toxic Dye Using Phytomediated Copper Nanoparticles and Its Free-Radical Scavenging Potential and Antimicrobial Activity against Environmental Pathogens |
| title_fullStr | Degradation of Toxic Dye Using Phytomediated Copper Nanoparticles and Its Free-Radical Scavenging Potential and Antimicrobial Activity against Environmental Pathogens |
| title_full_unstemmed | Degradation of Toxic Dye Using Phytomediated Copper Nanoparticles and Its Free-Radical Scavenging Potential and Antimicrobial Activity against Environmental Pathogens |
| title_short | Degradation of Toxic Dye Using Phytomediated Copper Nanoparticles and Its Free-Radical Scavenging Potential and Antimicrobial Activity against Environmental Pathogens |
| title_sort | degradation of toxic dye using phytomediated copper nanoparticles and its free radical scavenging potential and antimicrobial activity against environmental pathogens |
| url | http://dx.doi.org/10.1155/2021/1222908 |
| work_keys_str_mv | AT srajeshkumar degradationoftoxicdyeusingphytomediatedcoppernanoparticlesanditsfreeradicalscavengingpotentialandantimicrobialactivityagainstenvironmentalpathogens AT mvanaja degradationoftoxicdyeusingphytomediatedcoppernanoparticlesanditsfreeradicalscavengingpotentialandantimicrobialactivityagainstenvironmentalpathogens AT arunachalamkalirajan degradationoftoxicdyeusingphytomediatedcoppernanoparticlesanditsfreeradicalscavengingpotentialandantimicrobialactivityagainstenvironmentalpathogens |