Genetic diversity of Vif protein in human immunodeficiency virus type 1 variants (Retroviridae: <i>Orthoretrovirinae: Lentivirus: Human immunodeficiency virus-1</i>) that circulated in the Moscow region in 2019–2020

Genetic diversity of Vif protein in human immunodeficiency virus type 1 variants (Retroviridae: <i>Orthoretrovirinae: Lentivirus: Human immunodeficiency virus-1</i>) that circulated in the Moscow region in 2019–2020

Introduction. The Vif protein counteracts cellular deaminases, APOBEC3, which prevent viral replication. Vif is used for development of therapeutic agents. Natural polymorphisms in Vif can affect its functionality and may be associated with accelerated progression of HIV-infection to the AIDS. The s...

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Bibliographic Details
Main Authors: Anastasiia A. Antonova, Larisa A. Protasova, Kristina V. Kim, Iana M. Munchak, Ekaterina N. Mezhenskaya, Elena A. Orlova-Morozova, Alexander Yu. Pronin, Alexey G. Prilipov, Anna I. Kuznetsova
Format: Article
Language:English
Published: Central Research Institute for Epidemiology 2025-04-01
Series:Вопросы вирусологии
Subjects:
hiv-1
vif
sub-subtype а6
subtype в
crf63_02a6
Online Access:https://virusjour.crie.ru/jour/article/viewFile/16744/966
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