THE COURSE OF ACUTE RESPIRATORY COVID-19 DISEASE, COMPLICATED BY COMMUNITY-ACQUIRED PNEUMONIA AGAINST THE BACKGROUND OF THE CARDIOVASCULAR SYSTEM PATHOLOGY
The outbreak of the COVID-19 infection caused by the new coronavirus SARS-CoV-2 is one of the most significant and dangerous challenges of our time. To date, there is a decrease in the number of cases per day, but there is a variety in the course of the disease depending on sex, and the most vulnera...
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| Language: | English |
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Poltava State Medical University
2021-08-01
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| Series: | Проблеми екології та медицини |
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| Online Access: | https://ecomed-journal.org/index.php/journal/article/view/221 |
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| author | T.A. Trybrat Yu.M Kazakov O.O. Honcharova S.V Shut V.D. Sakevich |
| author_facet | T.A. Trybrat Yu.M Kazakov O.O. Honcharova S.V Shut V.D. Sakevich |
| author_sort | T.A. Trybrat |
| collection | DOAJ |
| description | The outbreak of the COVID-19 infection caused by the new coronavirus SARS-CoV-2 is one of the most significant and dangerous challenges of our time. To date, there is a decrease in the number of cases per day, but there is a variety in the course of the disease depending on sex, and the most vulnerable are elderly patients with comorbid pathology, therefore, the study of its features determines the relevance of this work. The aim of the research was to study the course of acute respiratory disease COVID-19, complicated by pneumonia, its gender features and the presence of a comorbid cardiovascular pathology. We examined 104 patients with acute respiratory COVID-19 disease, complicated by community-acquired pneumonia. We conducted general clinical methods of research, determined the SARS-CoV-2 virus RNA by PCR and chest X-ray in 2 projections or computed tomography (CT) to identify the features of the lung tissue damage. Among the cardiovascular pathology (35%) we observed coronary heart disease: stable angina pectoris FC (functional class) II-III - 85%, postinfarction cardiosclerosis - 30%, hypertension - 65%. Thus, a more pronounced intoxication syndrome of the variety of symptoms among women with acute respiratory COVID-19 disease, complicated by community-acquired pneumonia, is observed in women than in men, which must be taken into account, both in the diagnosis and treatment, assessment of prognosis of the development of the disease.
The presence of a comorbid pathology of the cardiovascular system complicated the course of the underlying disease. It had a more pronounced clinical course in a combination of two or more diseases and was characterized by progressive arrhythmias, subendocardial myocardial ischemia, volume overload of the left and right ventricles. A combination of several comorbid conditions was the most unfavorable for a patient, since it increased the risk of community-acquired pneumonia, was accompanied by its severe course with the development of complications and lethal outcome. |
| format | Article |
| id | doaj-art-aed5ddf6a80749119b1de2bdad82bc15 |
| institution | Kabale University |
| issn | 2073-4662 2519-2302 |
| language | English |
| publishDate | 2021-08-01 |
| publisher | Poltava State Medical University |
| record_format | Article |
| series | Проблеми екології та медицини |
| spelling | doaj-art-aed5ddf6a80749119b1de2bdad82bc152025-02-03T06:09:48ZengPoltava State Medical UniversityПроблеми екології та медицини2073-46622519-23022021-08-01253-4141710.31718/mep.2021.25.3-4.03221THE COURSE OF ACUTE RESPIRATORY COVID-19 DISEASE, COMPLICATED BY COMMUNITY-ACQUIRED PNEUMONIA AGAINST THE BACKGROUND OF THE CARDIOVASCULAR SYSTEM PATHOLOGYT.A. Trybrat0Yu.M Kazakov1O.O. Honcharova2S.V Shut3V.D. Sakevich4Полтавський державний медичний університет, Полтава, УкраїнаПолтавський державний медичний університет, Полтава, УкраїнаПолтавський державний медичний університет, Полтава, УкраїнаПолтавський державний медичний університет, Полтава, УкраїнаПолтавський державний медичний університет, Полтава, УкраїнаThe outbreak of the COVID-19 infection caused by the new coronavirus SARS-CoV-2 is one of the most significant and dangerous challenges of our time. To date, there is a decrease in the number of cases per day, but there is a variety in the course of the disease depending on sex, and the most vulnerable are elderly patients with comorbid pathology, therefore, the study of its features determines the relevance of this work. The aim of the research was to study the course of acute respiratory disease COVID-19, complicated by pneumonia, its gender features and the presence of a comorbid cardiovascular pathology. We examined 104 patients with acute respiratory COVID-19 disease, complicated by community-acquired pneumonia. We conducted general clinical methods of research, determined the SARS-CoV-2 virus RNA by PCR and chest X-ray in 2 projections or computed tomography (CT) to identify the features of the lung tissue damage. Among the cardiovascular pathology (35%) we observed coronary heart disease: stable angina pectoris FC (functional class) II-III - 85%, postinfarction cardiosclerosis - 30%, hypertension - 65%. Thus, a more pronounced intoxication syndrome of the variety of symptoms among women with acute respiratory COVID-19 disease, complicated by community-acquired pneumonia, is observed in women than in men, which must be taken into account, both in the diagnosis and treatment, assessment of prognosis of the development of the disease. The presence of a comorbid pathology of the cardiovascular system complicated the course of the underlying disease. It had a more pronounced clinical course in a combination of two or more diseases and was characterized by progressive arrhythmias, subendocardial myocardial ischemia, volume overload of the left and right ventricles. A combination of several comorbid conditions was the most unfavorable for a patient, since it increased the risk of community-acquired pneumonia, was accompanied by its severe course with the development of complications and lethal outcome.https://ecomed-journal.org/index.php/journal/article/view/221course, acute respiratory covid-19 disease, complications, community-acquired pneumonia, comorbidity, pathology of the cardiovascular system. |
| spellingShingle | T.A. Trybrat Yu.M Kazakov O.O. Honcharova S.V Shut V.D. Sakevich THE COURSE OF ACUTE RESPIRATORY COVID-19 DISEASE, COMPLICATED BY COMMUNITY-ACQUIRED PNEUMONIA AGAINST THE BACKGROUND OF THE CARDIOVASCULAR SYSTEM PATHOLOGY Проблеми екології та медицини course, acute respiratory covid-19 disease, complications, community-acquired pneumonia, comorbidity, pathology of the cardiovascular system. |
| title | THE COURSE OF ACUTE RESPIRATORY COVID-19 DISEASE, COMPLICATED BY COMMUNITY-ACQUIRED PNEUMONIA AGAINST THE BACKGROUND OF THE CARDIOVASCULAR SYSTEM PATHOLOGY |
| title_full | THE COURSE OF ACUTE RESPIRATORY COVID-19 DISEASE, COMPLICATED BY COMMUNITY-ACQUIRED PNEUMONIA AGAINST THE BACKGROUND OF THE CARDIOVASCULAR SYSTEM PATHOLOGY |
| title_fullStr | THE COURSE OF ACUTE RESPIRATORY COVID-19 DISEASE, COMPLICATED BY COMMUNITY-ACQUIRED PNEUMONIA AGAINST THE BACKGROUND OF THE CARDIOVASCULAR SYSTEM PATHOLOGY |
| title_full_unstemmed | THE COURSE OF ACUTE RESPIRATORY COVID-19 DISEASE, COMPLICATED BY COMMUNITY-ACQUIRED PNEUMONIA AGAINST THE BACKGROUND OF THE CARDIOVASCULAR SYSTEM PATHOLOGY |
| title_short | THE COURSE OF ACUTE RESPIRATORY COVID-19 DISEASE, COMPLICATED BY COMMUNITY-ACQUIRED PNEUMONIA AGAINST THE BACKGROUND OF THE CARDIOVASCULAR SYSTEM PATHOLOGY |
| title_sort | course of acute respiratory covid 19 disease complicated by community acquired pneumonia against the background of the cardiovascular system pathology |
| topic | course, acute respiratory covid-19 disease, complications, community-acquired pneumonia, comorbidity, pathology of the cardiovascular system. |
| url | https://ecomed-journal.org/index.php/journal/article/view/221 |
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