Efficacy of BAFF inhibition and B-cell depletion in non-obese diabetic mice as a spontaneous model for Sjögren’s disease

Efficacy of BAFF inhibition and B-cell depletion in non-obese diabetic mice as a spontaneous model for Sjögren’s disease

Introduction The therapeutic interest of targeting B-cell activating factor (BAFF) in Sjögren’s disease (SjD) can be suspected from the results of two phase II clinical trials but has not been evaluated in an animal model of the disease. We aimed to evaluate the therapeutic efficacy of this strategy...

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Main Authors: Renaud Felten, Jacques-Eric Gottenberg, Lucienne Chatenoud, Jean Sibilia, Pascal Schneider, Hélène Dumortier, Fanny Monneaux, Anne-Perrine Foray, Cindy Marquet, Coralie Pecquet, Fabrice Valette
Format: Article
Language:English
Published: BMJ Publishing Group 2024-09-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/10/3/e004112.full
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