Effect of Anodal Transcranial Direct Current Stimulation on Autism: A Randomized Double-Blind Crossover Trial
The aim of this study was to evaluate the Childhood Autism Rating Scale (CARS), Autism Treatment Evaluation Checklist (ATEC), and Children’s Global Assessment Scale (CGAS) after anodal transcranial direct current stimulation (tDCS) in individuals with autism. Twenty patients with autism received 5 c...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Behavioural Neurology |
| Online Access: | http://dx.doi.org/10.1155/2014/173073 |
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| author | Anuwat Amatachaya Narong Auvichayapat Niramol Patjanasoontorn Chanyut Suphakunpinyo Niran Ngernyam Benchaporn Aree-uea Keattichai Keeratitanont Paradee Auvichayapat |
| author_facet | Anuwat Amatachaya Narong Auvichayapat Niramol Patjanasoontorn Chanyut Suphakunpinyo Niran Ngernyam Benchaporn Aree-uea Keattichai Keeratitanont Paradee Auvichayapat |
| author_sort | Anuwat Amatachaya |
| collection | DOAJ |
| description | The aim of this study was to evaluate the Childhood Autism Rating Scale (CARS), Autism Treatment Evaluation Checklist (ATEC), and Children’s Global Assessment Scale (CGAS) after anodal transcranial direct current stimulation (tDCS) in individuals with autism. Twenty patients with autism received 5 consecutive days of both sham and active tDCS stimulation (1 mA) in a randomized double-blind crossover trial over the left dorsolateral prefrontal cortex (F3) for 20 minutes in different orders. Measures of CARS, ATEC, and CGAS were administered before treatment and at 7 days posttreatment. The result showed statistical decrease in CARS score (P<0.001). ATEC total was decreased from 67.25 to 58 (P<0.001). CGAS was increased at 7 days posttreatment (P=0.042). Our study suggests that anodal tDCS over the F3 may be a useful clinical tool in autism. |
| format | Article |
| id | doaj-art-aeb986bb4d254cfcb496ec5170bdeb53 |
| institution | Kabale University |
| issn | 0953-4180 1875-8584 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Behavioural Neurology |
| spelling | doaj-art-aeb986bb4d254cfcb496ec5170bdeb532025-02-03T00:59:00ZengWileyBehavioural Neurology0953-41801875-85842014-01-01201410.1155/2014/173073173073Effect of Anodal Transcranial Direct Current Stimulation on Autism: A Randomized Double-Blind Crossover TrialAnuwat Amatachaya0Narong Auvichayapat1Niramol Patjanasoontorn2Chanyut Suphakunpinyo3Niran Ngernyam4Benchaporn Aree-uea5Keattichai Keeratitanont6Paradee Auvichayapat7Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, ThailandDepartment of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, ThailandDepartment of Psychiatry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, ThailandDepartment of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, ThailandDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, ThailandDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, ThailandDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, ThailandDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, ThailandThe aim of this study was to evaluate the Childhood Autism Rating Scale (CARS), Autism Treatment Evaluation Checklist (ATEC), and Children’s Global Assessment Scale (CGAS) after anodal transcranial direct current stimulation (tDCS) in individuals with autism. Twenty patients with autism received 5 consecutive days of both sham and active tDCS stimulation (1 mA) in a randomized double-blind crossover trial over the left dorsolateral prefrontal cortex (F3) for 20 minutes in different orders. Measures of CARS, ATEC, and CGAS were administered before treatment and at 7 days posttreatment. The result showed statistical decrease in CARS score (P<0.001). ATEC total was decreased from 67.25 to 58 (P<0.001). CGAS was increased at 7 days posttreatment (P=0.042). Our study suggests that anodal tDCS over the F3 may be a useful clinical tool in autism.http://dx.doi.org/10.1155/2014/173073 |
| spellingShingle | Anuwat Amatachaya Narong Auvichayapat Niramol Patjanasoontorn Chanyut Suphakunpinyo Niran Ngernyam Benchaporn Aree-uea Keattichai Keeratitanont Paradee Auvichayapat Effect of Anodal Transcranial Direct Current Stimulation on Autism: A Randomized Double-Blind Crossover Trial Behavioural Neurology |
| title | Effect of Anodal Transcranial Direct Current Stimulation on Autism: A Randomized Double-Blind Crossover Trial |
| title_full | Effect of Anodal Transcranial Direct Current Stimulation on Autism: A Randomized Double-Blind Crossover Trial |
| title_fullStr | Effect of Anodal Transcranial Direct Current Stimulation on Autism: A Randomized Double-Blind Crossover Trial |
| title_full_unstemmed | Effect of Anodal Transcranial Direct Current Stimulation on Autism: A Randomized Double-Blind Crossover Trial |
| title_short | Effect of Anodal Transcranial Direct Current Stimulation on Autism: A Randomized Double-Blind Crossover Trial |
| title_sort | effect of anodal transcranial direct current stimulation on autism a randomized double blind crossover trial |
| url | http://dx.doi.org/10.1155/2014/173073 |
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