Multimodal Imaging of Subfoveal Pachydrusen Containing a Blood Flow Signal

Individuals with pachydrusen, larger than 125 μm, have a significantly thicker choroid than do those with soft drusen or reticular pseudodrusen. Little is known about cases of abnormal blood flow within pachydrusen. The purpose of this report was to demonstrate a blood flow signal within pachydrusen...

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Main Authors: Naoko Ishiguro, Takaaki Hayashi, Yoshiko Yamawaki, Kei Mizobuchi, Tsutomu Yasukawa, Shigeru Honda, Tadashi Nakano
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2022/5680913
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author Naoko Ishiguro
Takaaki Hayashi
Yoshiko Yamawaki
Kei Mizobuchi
Tsutomu Yasukawa
Shigeru Honda
Tadashi Nakano
author_facet Naoko Ishiguro
Takaaki Hayashi
Yoshiko Yamawaki
Kei Mizobuchi
Tsutomu Yasukawa
Shigeru Honda
Tadashi Nakano
author_sort Naoko Ishiguro
collection DOAJ
description Individuals with pachydrusen, larger than 125 μm, have a significantly thicker choroid than do those with soft drusen or reticular pseudodrusen. Little is known about cases of abnormal blood flow within pachydrusen. The purpose of this report was to demonstrate a blood flow signal within pachydrusen using optical coherence tomography (OCT) angiography. A 76-year-old Japanese woman presented with innumerable drusen/pachydrusen in both posterior poles. Her visual acuity was good. OCT showed subfoveal pachydrusen in the left eye, but no exudative changes. The subfoveal choroidal thickness was increased to 274 μm in the left eye. OCT angiography revealed a blood flow signal within the pachydrusen. However, fluorescein and indocyanine green angiographies indicated no abnormal hyperfluorescent lesion in the macula of the left eye. During the 13-month follow-up, the blood flow signal in OCT angiography did not change in diameter, and no exudative change was observed. The blood flow signal may have properties of capillary blood vessels derived from the choriocapillaris, rather than angiogenic vessels from choroidal neovascularization or polypoidal choroidal vasculopathy/aneurysmal type 1 neovascularization.
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institution Kabale University
issn 2090-6730
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publishDate 2022-01-01
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series Case Reports in Ophthalmological Medicine
spelling doaj-art-aea8c8eda33d46cd8fade42483da47922025-02-03T05:50:00ZengWileyCase Reports in Ophthalmological Medicine2090-67302022-01-01202210.1155/2022/5680913Multimodal Imaging of Subfoveal Pachydrusen Containing a Blood Flow SignalNaoko Ishiguro0Takaaki Hayashi1Yoshiko Yamawaki2Kei Mizobuchi3Tsutomu Yasukawa4Shigeru Honda5Tadashi Nakano6Department of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyDepartment of Ophthalmology and Visual ScienceDepartment of Ophthalmology and Visual SciencesDepartment of OphthalmologyIndividuals with pachydrusen, larger than 125 μm, have a significantly thicker choroid than do those with soft drusen or reticular pseudodrusen. Little is known about cases of abnormal blood flow within pachydrusen. The purpose of this report was to demonstrate a blood flow signal within pachydrusen using optical coherence tomography (OCT) angiography. A 76-year-old Japanese woman presented with innumerable drusen/pachydrusen in both posterior poles. Her visual acuity was good. OCT showed subfoveal pachydrusen in the left eye, but no exudative changes. The subfoveal choroidal thickness was increased to 274 μm in the left eye. OCT angiography revealed a blood flow signal within the pachydrusen. However, fluorescein and indocyanine green angiographies indicated no abnormal hyperfluorescent lesion in the macula of the left eye. During the 13-month follow-up, the blood flow signal in OCT angiography did not change in diameter, and no exudative change was observed. The blood flow signal may have properties of capillary blood vessels derived from the choriocapillaris, rather than angiogenic vessels from choroidal neovascularization or polypoidal choroidal vasculopathy/aneurysmal type 1 neovascularization.http://dx.doi.org/10.1155/2022/5680913
spellingShingle Naoko Ishiguro
Takaaki Hayashi
Yoshiko Yamawaki
Kei Mizobuchi
Tsutomu Yasukawa
Shigeru Honda
Tadashi Nakano
Multimodal Imaging of Subfoveal Pachydrusen Containing a Blood Flow Signal
Case Reports in Ophthalmological Medicine
title Multimodal Imaging of Subfoveal Pachydrusen Containing a Blood Flow Signal
title_full Multimodal Imaging of Subfoveal Pachydrusen Containing a Blood Flow Signal
title_fullStr Multimodal Imaging of Subfoveal Pachydrusen Containing a Blood Flow Signal
title_full_unstemmed Multimodal Imaging of Subfoveal Pachydrusen Containing a Blood Flow Signal
title_short Multimodal Imaging of Subfoveal Pachydrusen Containing a Blood Flow Signal
title_sort multimodal imaging of subfoveal pachydrusen containing a blood flow signal
url http://dx.doi.org/10.1155/2022/5680913
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