Prophylaxis Against Mycobacterium avium Complex Infection in AIDS

Disseminated Mycobacterium avium complex (MAC) infection in AIDS is increasing in frequency, although it remains under-recognized due to unlocalized clinical manifestations and subtle initial presentation, if not the need for specialized laboratory diagnostic methods. Ultimately, MAC accounts for mu...

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Main Author: DW Cameron
Format: Article
Language:English
Published: Wiley 1994-01-01
Series:Canadian Journal of Infectious Diseases
Online Access:http://dx.doi.org/10.1155/1994/587182
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author DW Cameron
author_facet DW Cameron
author_sort DW Cameron
collection DOAJ
description Disseminated Mycobacterium avium complex (MAC) infection in AIDS is increasing in frequency, although it remains under-recognized due to unlocalized clinical manifestations and subtle initial presentation, if not the need for specialized laboratory diagnostic methods. Ultimately, MAC accounts for much of the “wasting syndrome” in the natural history of human immunodeficiency virus disease. Multidrug treatment of MAC in AIDS is problematic. That MAC is preventable has been demonstrated, and how much clinical benefit can be had from successful prophylaxis remains to be evaluated in the face of improved efficacy of both treatment and prophylaxis regimens under investigation.
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institution Kabale University
issn 1180-2332
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spelling doaj-art-aea053fa430a4ca1b1847227c1a96afb2025-02-03T05:46:59ZengWileyCanadian Journal of Infectious Diseases1180-23321994-01-015Suppl B10B13B10.1155/1994/587182Prophylaxis Against Mycobacterium avium Complex Infection in AIDSDW Cameron0Canadian HN Trials Network - Ontario Region, Ottawa, Ontmio, CanadaDisseminated Mycobacterium avium complex (MAC) infection in AIDS is increasing in frequency, although it remains under-recognized due to unlocalized clinical manifestations and subtle initial presentation, if not the need for specialized laboratory diagnostic methods. Ultimately, MAC accounts for much of the “wasting syndrome” in the natural history of human immunodeficiency virus disease. Multidrug treatment of MAC in AIDS is problematic. That MAC is preventable has been demonstrated, and how much clinical benefit can be had from successful prophylaxis remains to be evaluated in the face of improved efficacy of both treatment and prophylaxis regimens under investigation.http://dx.doi.org/10.1155/1994/587182
spellingShingle DW Cameron
Prophylaxis Against Mycobacterium avium Complex Infection in AIDS
Canadian Journal of Infectious Diseases
title Prophylaxis Against Mycobacterium avium Complex Infection in AIDS
title_full Prophylaxis Against Mycobacterium avium Complex Infection in AIDS
title_fullStr Prophylaxis Against Mycobacterium avium Complex Infection in AIDS
title_full_unstemmed Prophylaxis Against Mycobacterium avium Complex Infection in AIDS
title_short Prophylaxis Against Mycobacterium avium Complex Infection in AIDS
title_sort prophylaxis against mycobacterium avium complex infection in aids
url http://dx.doi.org/10.1155/1994/587182
work_keys_str_mv AT dwcameron prophylaxisagainstmycobacteriumaviumcomplexinfectioninaids