HPRNA: Predicting synergistic drug combinations for angina pectoris based on human pathway relationship network algorithm.

HPRNA: Predicting synergistic drug combinations for angina pectoris based on human pathway relationship network algorithm.

Over the years, synergistic drug combinations therapies have attracted widespread attention due to its advantages of overcoming drug resistance, increasing treatment efficacy and decreasing toxicity. Compared to lengthy medical drugs experimental screening, mathematical models and algorithms show gr...

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Bibliographic Details
Main Authors: Mengyao Zhou, Mengfan Xu, Xiangling Zhang, Xiaochun Xing, Yang Li, Guanghui Wang, Guiying Yan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0318368
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