The complexity of caffeine's effects on regular coffee consumers

Why does coffee wake us up? Is it because it contains caffeine, or because we are used to it waking us up after drinking it? To answer this question, we recruited twenty habitual coffee drinkers who received either caffeinated or decaffeinated coffee (placebo) in a double-blind, randomized fashion....

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Main Authors: Mateja Lesar, Jakob Sajovic, Dušanka Novaković, Maša Primožič, Eva Vetrih, Martin Sajovic, Anja Žnidaršič, Peter Rogelj, Andreas Daffertshofer, Zoran Levnajić, Gorazd Drevenšek
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Heliyon
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024175020
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author Mateja Lesar
Jakob Sajovic
Dušanka Novaković
Maša Primožič
Eva Vetrih
Martin Sajovic
Anja Žnidaršič
Peter Rogelj
Andreas Daffertshofer
Zoran Levnajić
Gorazd Drevenšek
author_facet Mateja Lesar
Jakob Sajovic
Dušanka Novaković
Maša Primožič
Eva Vetrih
Martin Sajovic
Anja Žnidaršič
Peter Rogelj
Andreas Daffertshofer
Zoran Levnajić
Gorazd Drevenšek
author_sort Mateja Lesar
collection DOAJ
description Why does coffee wake us up? Is it because it contains caffeine, or because we are used to it waking us up after drinking it? To answer this question, we recruited twenty habitual coffee drinkers who received either caffeinated or decaffeinated coffee (placebo) in a double-blind, randomized fashion. The two substances were identical except for the presence of caffeine. We measured cognitive performance, cardiovascular responses, and whole-head EEG during rest and during an auditory-oddball task. The same measurements were done before and after ingestion. We expected to find significant differences between caffeine and placebo groups across the outcome measures. However, except for the resting-state alpha power, changes due to ingestion in physiological responses and in cognitive functioning were not significantly different between the two groups. Actually, only one of the three cognitive measures was found to be significantly altered by the ingestion. These findings suggest that regular coffee consumers respond to coffee-like beverages independently of the presence of caffeine.
format Article
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institution Kabale University
issn 2405-8440
language English
publishDate 2025-01-01
publisher Elsevier
record_format Article
series Heliyon
spelling doaj-art-ae9d1170fbab4f088134e26854217f7d2025-02-02T05:27:48ZengElsevierHeliyon2405-84402025-01-01112e41471The complexity of caffeine's effects on regular coffee consumersMateja Lesar0Jakob Sajovic1Dušanka Novaković2Maša Primožič3Eva Vetrih4Martin Sajovic5Anja Žnidaršič6Peter Rogelj7Andreas Daffertshofer8Zoran Levnajić9Gorazd Drevenšek10Faculty of Information Studies in Novo mesto, Slovenia; Corresponding author.University Medical Centre Ljubljana, SloveniaFaculty of Information Studies in Novo mesto, SloveniaFaculty of Mathematics, Natural Sciences and Information Technologies, University of Primorska, Koper, SloveniaUniversity Medical Centre Ljubljana, SloveniaHigher Vocational School Kranj, SloveniaFaculty of Organizational Sciences, University of Maribor, SloveniaFaculty of Mathematics, Natural Sciences and Information Technologies, University of Primorska, Koper, SloveniaFaculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, the NetherlandsFaculty of Information Studies in Novo mesto, SloveniaThe Institute of Pharmacology and Experimental Toxicology, Faculty of Medicine, University of Ljubljana, SloveniaWhy does coffee wake us up? Is it because it contains caffeine, or because we are used to it waking us up after drinking it? To answer this question, we recruited twenty habitual coffee drinkers who received either caffeinated or decaffeinated coffee (placebo) in a double-blind, randomized fashion. The two substances were identical except for the presence of caffeine. We measured cognitive performance, cardiovascular responses, and whole-head EEG during rest and during an auditory-oddball task. The same measurements were done before and after ingestion. We expected to find significant differences between caffeine and placebo groups across the outcome measures. However, except for the resting-state alpha power, changes due to ingestion in physiological responses and in cognitive functioning were not significantly different between the two groups. Actually, only one of the three cognitive measures was found to be significantly altered by the ingestion. These findings suggest that regular coffee consumers respond to coffee-like beverages independently of the presence of caffeine.http://www.sciencedirect.com/science/article/pii/S2405844024175020
spellingShingle Mateja Lesar
Jakob Sajovic
Dušanka Novaković
Maša Primožič
Eva Vetrih
Martin Sajovic
Anja Žnidaršič
Peter Rogelj
Andreas Daffertshofer
Zoran Levnajić
Gorazd Drevenšek
The complexity of caffeine's effects on regular coffee consumers
Heliyon
title The complexity of caffeine's effects on regular coffee consumers
title_full The complexity of caffeine's effects on regular coffee consumers
title_fullStr The complexity of caffeine's effects on regular coffee consumers
title_full_unstemmed The complexity of caffeine's effects on regular coffee consumers
title_short The complexity of caffeine's effects on regular coffee consumers
title_sort complexity of caffeine s effects on regular coffee consumers
url http://www.sciencedirect.com/science/article/pii/S2405844024175020
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