Synthesis, Characterization and Anticancer Activity of Poly Acetal /PVP Ag, Au Nanocomposite in Treatment of Lung Cancer Cell Line
In this research, poly acetal has been prepared from poly vinyl alcohol reaction with the para methyl benzaldehyde. The solution casting process was used to create the polymer blends of poly acetal and PVP. The aim of this study is to investigate the influence of the gold and silver nanopartic...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
University of Baghdad
2025-01-01
|
| Series: | Ibn Al-Haitham Journal for Pure and Applied Sciences |
| Subjects: | |
| Online Access: | https://jih.uobaghdad.edu.iq/index.php/j/article/view/3607 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832592022083469312 |
|---|---|
| author | Maha A. Younus Dalia J. Hadi |
| author_facet | Maha A. Younus Dalia J. Hadi |
| author_sort | Maha A. Younus |
| collection | DOAJ |
| description |
In this research, poly acetal has been prepared from poly vinyl alcohol reaction with the para methyl benzaldehyde. The solution casting process was used to create the polymer blends of poly acetal and PVP. The aim of this study is to investigate the influence of the gold and silver nanoparticles on the anticancer activity of the prepared compounds. Using onion peel extract as a reducing agent, the gold nanoparticles (AuNPs) and silver nanoparticles (AgNPs) were created. Nanocomposite were prepared by solution casting by mixing poly acetal /PVP /Au, Ag nano particles with different ratios. The AuNPs And AgNPs were characterized through XRD analysis and FESEM microscopy. The poly acetal, polymer blends and nano composite were characterized by FTIR, FESEM, DSC and TGA. The FTIR has been used to analyze poly acetal, which confirms its production by displaying a new band of absorption at 1105 cm-1 due to the (O-C-O). The thermal stability of the generated polymer blends and nanocomposites is confirmed by DSC and TGA; in comparison to blends, nanocomposites have demonstrated good performance in suppressing lung cancer cell lines.
|
| format | Article |
| id | doaj-art-ae96f736dad2420489721746bad15adf |
| institution | Kabale University |
| issn | 1609-4042 2521-3407 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | University of Baghdad |
| record_format | Article |
| series | Ibn Al-Haitham Journal for Pure and Applied Sciences |
| spelling | doaj-art-ae96f736dad2420489721746bad15adf2025-01-22T01:21:06ZengUniversity of BaghdadIbn Al-Haitham Journal for Pure and Applied Sciences1609-40422521-34072025-01-0138110.30526/38.1.3607Synthesis, Characterization and Anticancer Activity of Poly Acetal /PVP Ag, Au Nanocomposite in Treatment of Lung Cancer Cell LineMaha A. Younus0https://orcid.org/0000-0002-4155-7978Dalia J. Hadi 1https://orcid.org/0009-0001-5224-4520Department of Chemistry, College of Education for pure Sciences (Ibn AL-Haitham) University of BaghdadDepartment of Chemistry, College of Education for pure Sciences (Ibn AL-Haitham) University of Baghdad, Baghdad, Iraq. In this research, poly acetal has been prepared from poly vinyl alcohol reaction with the para methyl benzaldehyde. The solution casting process was used to create the polymer blends of poly acetal and PVP. The aim of this study is to investigate the influence of the gold and silver nanoparticles on the anticancer activity of the prepared compounds. Using onion peel extract as a reducing agent, the gold nanoparticles (AuNPs) and silver nanoparticles (AgNPs) were created. Nanocomposite were prepared by solution casting by mixing poly acetal /PVP /Au, Ag nano particles with different ratios. The AuNPs And AgNPs were characterized through XRD analysis and FESEM microscopy. The poly acetal, polymer blends and nano composite were characterized by FTIR, FESEM, DSC and TGA. The FTIR has been used to analyze poly acetal, which confirms its production by displaying a new band of absorption at 1105 cm-1 due to the (O-C-O). The thermal stability of the generated polymer blends and nanocomposites is confirmed by DSC and TGA; in comparison to blends, nanocomposites have demonstrated good performance in suppressing lung cancer cell lines. https://jih.uobaghdad.edu.iq/index.php/j/article/view/3607Anti-cancer cell linePVPpolyacetalnanocomposite |
| spellingShingle | Maha A. Younus Dalia J. Hadi Synthesis, Characterization and Anticancer Activity of Poly Acetal /PVP Ag, Au Nanocomposite in Treatment of Lung Cancer Cell Line Ibn Al-Haitham Journal for Pure and Applied Sciences Anti-cancer cell line PVP polyacetal nanocomposite |
| title | Synthesis, Characterization and Anticancer Activity of Poly Acetal /PVP Ag, Au Nanocomposite in Treatment of Lung Cancer Cell Line |
| title_full | Synthesis, Characterization and Anticancer Activity of Poly Acetal /PVP Ag, Au Nanocomposite in Treatment of Lung Cancer Cell Line |
| title_fullStr | Synthesis, Characterization and Anticancer Activity of Poly Acetal /PVP Ag, Au Nanocomposite in Treatment of Lung Cancer Cell Line |
| title_full_unstemmed | Synthesis, Characterization and Anticancer Activity of Poly Acetal /PVP Ag, Au Nanocomposite in Treatment of Lung Cancer Cell Line |
| title_short | Synthesis, Characterization and Anticancer Activity of Poly Acetal /PVP Ag, Au Nanocomposite in Treatment of Lung Cancer Cell Line |
| title_sort | synthesis characterization and anticancer activity of poly acetal pvp ag au nanocomposite in treatment of lung cancer cell line |
| topic | Anti-cancer cell line PVP polyacetal nanocomposite |
| url | https://jih.uobaghdad.edu.iq/index.php/j/article/view/3607 |
| work_keys_str_mv | AT mahaayounus synthesischaracterizationandanticanceractivityofpolyacetalpvpagaunanocompositeintreatmentoflungcancercellline AT daliajhadi synthesischaracterizationandanticanceractivityofpolyacetalpvpagaunanocompositeintreatmentoflungcancercellline |