Maternal and Perinatal Outcomes in Women with Polycystic Ovary Syndrome Undergoing Artificial Frozen-Thawed Embryo Transfer Cycles: A Retrospective Study

Background: Polycystic ovary syndrome (PCOS) is a worldwide endocrine disorder of reproductive-aged women. In addition to infertility, PCOS may lead to unfavorable maternal and prenatal outcomes in assisted reproductive technology cycles. The aim of the study was to investigate the risk of adverse m...

Full description

Saved in:
Bibliographic Details
Main Authors: Saeideh Dashti, Maryam Eftekhar, Danial Sarikhani, Nasim Tabibnejad
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Advanced Biomedical Research
Subjects:
Online Access:https://journals.lww.com/10.4103/abr.abr_128_24
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832086872340299776
author Saeideh Dashti
Maryam Eftekhar
Danial Sarikhani
Nasim Tabibnejad
author_facet Saeideh Dashti
Maryam Eftekhar
Danial Sarikhani
Nasim Tabibnejad
author_sort Saeideh Dashti
collection DOAJ
description Background: Polycystic ovary syndrome (PCOS) is a worldwide endocrine disorder of reproductive-aged women. In addition to infertility, PCOS may lead to unfavorable maternal and prenatal outcomes in assisted reproductive technology cycles. The aim of the study was to investigate the risk of adverse maternal and perinatal outcomes using frozen-thawed embryo transfer (FET) among women with and without PCOS. Materials and Methods: The data of 1064 women in the PCOS group and 1473 women in the control group were analyzed after FET. Adverse maternal and prenatal outcomes including gestational diabetes mellitus, pre-eclampsia, premature rupture of membranes, preterm birth, low birth weight, and stillbirth were compared between the two groups. Results: We did not find significant differences in the above-mentioned variables between the two groups. Gestational diabetes (7.1% vs. 11%), pre-eclampsia (12% vs. 11.8%), premature rupture of membranes (3.8% vs. 6.5%), preterm birth (13% vs. 15.9%), and low birth weight (10.9% vs. 14.7%) between PCOS and non-PCOS groups, respectively (P > 0.05). Conclusions: Our result showed that there are no differences between PCOS and non-PCOS women undergoing FET regarding maternal and neonatal outcomes.
format Article
id doaj-art-ae5b4066c0274be4870cff30ec6410cf
institution Kabale University
issn 2277-9175
language English
publishDate 2025-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Advanced Biomedical Research
spelling doaj-art-ae5b4066c0274be4870cff30ec6410cf2025-02-06T09:41:42ZengWolters Kluwer Medknow PublicationsAdvanced Biomedical Research2277-91752025-01-011413310.4103/abr.abr_128_24Maternal and Perinatal Outcomes in Women with Polycystic Ovary Syndrome Undergoing Artificial Frozen-Thawed Embryo Transfer Cycles: A Retrospective StudySaeideh DashtiMaryam EftekharDanial SarikhaniNasim TabibnejadBackground: Polycystic ovary syndrome (PCOS) is a worldwide endocrine disorder of reproductive-aged women. In addition to infertility, PCOS may lead to unfavorable maternal and prenatal outcomes in assisted reproductive technology cycles. The aim of the study was to investigate the risk of adverse maternal and perinatal outcomes using frozen-thawed embryo transfer (FET) among women with and without PCOS. Materials and Methods: The data of 1064 women in the PCOS group and 1473 women in the control group were analyzed after FET. Adverse maternal and prenatal outcomes including gestational diabetes mellitus, pre-eclampsia, premature rupture of membranes, preterm birth, low birth weight, and stillbirth were compared between the two groups. Results: We did not find significant differences in the above-mentioned variables between the two groups. Gestational diabetes (7.1% vs. 11%), pre-eclampsia (12% vs. 11.8%), premature rupture of membranes (3.8% vs. 6.5%), preterm birth (13% vs. 15.9%), and low birth weight (10.9% vs. 14.7%) between PCOS and non-PCOS groups, respectively (P > 0.05). Conclusions: Our result showed that there are no differences between PCOS and non-PCOS women undergoing FET regarding maternal and neonatal outcomes.https://journals.lww.com/10.4103/abr.abr_128_24embryo transfermaternaloutcomesperinatalpolycystic ovary syndrome
spellingShingle Saeideh Dashti
Maryam Eftekhar
Danial Sarikhani
Nasim Tabibnejad
Maternal and Perinatal Outcomes in Women with Polycystic Ovary Syndrome Undergoing Artificial Frozen-Thawed Embryo Transfer Cycles: A Retrospective Study
Advanced Biomedical Research
embryo transfer
maternal
outcomes
perinatal
polycystic ovary syndrome
title Maternal and Perinatal Outcomes in Women with Polycystic Ovary Syndrome Undergoing Artificial Frozen-Thawed Embryo Transfer Cycles: A Retrospective Study
title_full Maternal and Perinatal Outcomes in Women with Polycystic Ovary Syndrome Undergoing Artificial Frozen-Thawed Embryo Transfer Cycles: A Retrospective Study
title_fullStr Maternal and Perinatal Outcomes in Women with Polycystic Ovary Syndrome Undergoing Artificial Frozen-Thawed Embryo Transfer Cycles: A Retrospective Study
title_full_unstemmed Maternal and Perinatal Outcomes in Women with Polycystic Ovary Syndrome Undergoing Artificial Frozen-Thawed Embryo Transfer Cycles: A Retrospective Study
title_short Maternal and Perinatal Outcomes in Women with Polycystic Ovary Syndrome Undergoing Artificial Frozen-Thawed Embryo Transfer Cycles: A Retrospective Study
title_sort maternal and perinatal outcomes in women with polycystic ovary syndrome undergoing artificial frozen thawed embryo transfer cycles a retrospective study
topic embryo transfer
maternal
outcomes
perinatal
polycystic ovary syndrome
url https://journals.lww.com/10.4103/abr.abr_128_24
work_keys_str_mv AT saeidehdashti maternalandperinataloutcomesinwomenwithpolycysticovarysyndromeundergoingartificialfrozenthawedembryotransfercyclesaretrospectivestudy
AT maryameftekhar maternalandperinataloutcomesinwomenwithpolycysticovarysyndromeundergoingartificialfrozenthawedembryotransfercyclesaretrospectivestudy
AT danialsarikhani maternalandperinataloutcomesinwomenwithpolycysticovarysyndromeundergoingartificialfrozenthawedembryotransfercyclesaretrospectivestudy
AT nasimtabibnejad maternalandperinataloutcomesinwomenwithpolycysticovarysyndromeundergoingartificialfrozenthawedembryotransfercyclesaretrospectivestudy