HDAC6 Facilitates PRV and VSV Infection by Inhibiting Type I Interferon Production

HDAC6 Facilitates PRV and VSV Infection by Inhibiting Type I Interferon Production

HDAC6 modulates viral infection through diverse mechanisms. Here, we investigated the role of HDAC6 in influencing viral infection in pig cells with the aim of exploiting the potential antiviral gene targets in pigs. Using gene knockout and overexpression strategies, we found that HDAC6 knockout gre...

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Bibliographic Details
Main Authors: Hu Zheng, Xiaohui Yang, Haiwen Zhong, Changxu Song, Zhenfang Wu, Huaqiang Yang
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Viruses
Subjects:
HDAC6
PRV
VSV
Type I IFN
antiviral immunity
host-virus interaction
Online Access:https://www.mdpi.com/1999-4915/17/1/90
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