Menin facilitates the cell proliferation of bladder cancer via modulating the TFAP2C/β-catenin axis

Menin facilitates the cell proliferation of bladder cancer via modulating the TFAP2C/β-catenin axis

Bladder cancer (BLCA) is a common malignant tumor of the urinary system, with significant morbidity and mortality rates worldwide. The MEN1 gene, encoding the menin protein, plays a regulatory role in several cancers. However, the role played by menin in BLCA remains elusive. In this study, our data...

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Bibliographic Details
Main Authors: Qing Shi, Xiang Pan, Shiheng Zhang, Mengyuan Wu, Meiqi Xu, Yun-Qi Li, Li Zhong, Zi-Qi Wang, Wanhai Xu, Yakun Luo
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-11-01
Series:Genes and Diseases
Subjects:
β-catenin
Bladder cancer
Cell proliferation
MEN1
TFAP2C
Therapeutic target
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304225000546
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