Application of autogenous vaccine in bitches with transmissible venereal tumor
<b>Aim:</b> The aim of the study was to determine the success of autogenous vaccine application in treatment of TVT.<p> <b>Materials and Methods:</b> The study was conducted on 8 bitches with TVT. . The autogenous vaccine applied on the dogs was maddened the based on th...
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| Format: | Article |
| Language: | English |
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Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
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| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=974 |
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| author | Sakine Ülküm Çizmeci Ayşe Merve Köse İbrahim Aydın Dursun Ali Dinç Mehmet Maden Serkan İrfan Köse |
| author_facet | Sakine Ülküm Çizmeci Ayşe Merve Köse İbrahim Aydın Dursun Ali Dinç Mehmet Maden Serkan İrfan Köse |
| author_sort | Sakine Ülküm Çizmeci |
| collection | DOAJ |
| description | <b>Aim:</b> The aim of the study was to determine the success of
autogenous vaccine application in treatment of TVT.<p>
<b>Materials and Methods:</b> The study was conducted on 8
bitches with TVT. . The autogenous vaccine applied on the
dogs was maddened the based on the bovine papillomatosis
vaccine. Approximately 24 g of tumor tissue and 48 mL
Tris buffer (pH 7.5) solution were crushed in cold conditions
(+4 0C) during 15-20 minutes in mortar disintegrated
with autoclaved sterile sand. Half of the mixture (36 mL)
was completed with tris buffer to 60-65 mL. 0.5 percent formalin
was added this mixture and mixture was portioned to
6 each has 10 mL. The prepared vaccine was administered
4 times (SC) with an interval of 1 week. Dogs were followed
up 3 months after 4th application and evaluations were performed
for tumor regression.<p>
<b>Results:</b> Serosanguineous or hemorrhagic genital discharge
was determined in dogs prior to application of autogenous
vaccine. The lesions in external genital organs are
like cauliflower, rubescent, fresh-looking and easily bleed
on touched. After administration of the autogenous vaccine,
serosanguineous or hemorrhagic genital discharge from
the masses on the external genital organs of dogs continued,
and there were no changes in the mass fragility. After
the application of autogenous vaccines at four times, there
was no any decline and improvement in the masses on the
vagina and vulva.<p>
<b>Conclusions:</b> It is believed that a viral agent may contribute
to the etiology of TVT. Prepared autogenous vaccine
technique used in the treatment of bovine papillomatosis
derived from bovine papilloma virus may not be suitable in
the treatment of bitches with TVT. |
| format | Article |
| id | doaj-art-ae33824458b54173b44848412dad2044 |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-ae33824458b54173b44848412dad20442025-02-03T11:25:41ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-1953284220223974Application of autogenous vaccine in bitches with transmissible venereal tumorSakine Ülküm Çizmeci0Ayşe Merve Köse1İbrahim Aydın2Dursun Ali Dinç3Mehmet Maden4Serkan İrfan Köse5Doğum ve Jinekoloji Anabilim Dalı, Veteriner Fakültesi, Selçuk Üniversitesi, Kampüs, Konya, TürkiyeDoğum ve Jinekoloji Anabilim Dalı, Veteriner Fakültesi, Selçuk Üniversitesi, Kampüs, Konya, TürkiyeDoğum ve Jinekoloji Anabilim Dalı, Veteriner Fakültesi, Selçuk Üniversitesi, Kampüs, Konya, TürkiyeDoğum ve Jinekoloji Anabilim Dalı, Veteriner Fakültesi, Selçuk Üniversitesi, Kampüs, Konya, Türkiyeİç Hastalıkları Anabilim Dalı, Veteriner Fakültesi, Selçuk Üniversitesi, Kampüs, Konya, Türkiyeİç Hastalıkları Anabilim Dalı, Veteriner Fakültesi, Selçuk Üniversitesi, Kampüs, Konya, Türkiye<b>Aim:</b> The aim of the study was to determine the success of autogenous vaccine application in treatment of TVT.<p> <b>Materials and Methods:</b> The study was conducted on 8 bitches with TVT. . The autogenous vaccine applied on the dogs was maddened the based on the bovine papillomatosis vaccine. Approximately 24 g of tumor tissue and 48 mL Tris buffer (pH 7.5) solution were crushed in cold conditions (+4 0C) during 15-20 minutes in mortar disintegrated with autoclaved sterile sand. Half of the mixture (36 mL) was completed with tris buffer to 60-65 mL. 0.5 percent formalin was added this mixture and mixture was portioned to 6 each has 10 mL. The prepared vaccine was administered 4 times (SC) with an interval of 1 week. Dogs were followed up 3 months after 4th application and evaluations were performed for tumor regression.<p> <b>Results:</b> Serosanguineous or hemorrhagic genital discharge was determined in dogs prior to application of autogenous vaccine. The lesions in external genital organs are like cauliflower, rubescent, fresh-looking and easily bleed on touched. After administration of the autogenous vaccine, serosanguineous or hemorrhagic genital discharge from the masses on the external genital organs of dogs continued, and there were no changes in the mass fragility. After the application of autogenous vaccines at four times, there was no any decline and improvement in the masses on the vagina and vulva.<p> <b>Conclusions:</b> It is believed that a viral agent may contribute to the etiology of TVT. Prepared autogenous vaccine technique used in the treatment of bovine papillomatosis derived from bovine papilloma virus may not be suitable in the treatment of bitches with TVT.http://eurasianjvetsci.org/pdf.php3?id=974transmissible venereal tumorautogenous vaccine |
| spellingShingle | Sakine Ülküm Çizmeci Ayşe Merve Köse İbrahim Aydın Dursun Ali Dinç Mehmet Maden Serkan İrfan Köse Application of autogenous vaccine in bitches with transmissible venereal tumor Eurasian Journal of Veterinary Sciences transmissible venereal tumor autogenous vaccine |
| title | Application of autogenous vaccine in bitches with transmissible venereal tumor |
| title_full | Application of autogenous vaccine in bitches with transmissible venereal tumor |
| title_fullStr | Application of autogenous vaccine in bitches with transmissible venereal tumor |
| title_full_unstemmed | Application of autogenous vaccine in bitches with transmissible venereal tumor |
| title_short | Application of autogenous vaccine in bitches with transmissible venereal tumor |
| title_sort | application of autogenous vaccine in bitches with transmissible venereal tumor |
| topic | transmissible venereal tumor autogenous vaccine |
| url | http://eurasianjvetsci.org/pdf.php3?id=974 |
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