A model of drug resistance with infection by health care workers
Antibiotic resistant organisms (ARO) pose an increasing seriousthreat in hospitals. One of the most life threatening ARO ismethicillin-resistant staphylococcus aureus (MRSA). In this paper,we introduced a new mathematical model which focuses on theevolution of two bacterial strains, drug-resistant a...
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| Format: | Article |
| Language: | English |
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AIMS Press
2010-09-01
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| Series: | Mathematical Biosciences and Engineering |
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| Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2010.7.779 |
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| author | Avner Friedman Najat Ziyadi Khalid Boushaba |
| author_facet | Avner Friedman Najat Ziyadi Khalid Boushaba |
| author_sort | Avner Friedman |
| collection | DOAJ |
| description | Antibiotic resistant organisms (ARO) pose an increasing seriousthreat in hospitals. One of the most life threatening ARO ismethicillin-resistant staphylococcus aureus (MRSA). In this paper,we introduced a new mathematical model which focuses on theevolution of two bacterial strains, drug-resistant and non-drugresistant, residing within the population of patients and healthcare workers in a hospital. The model predicts that as soon as drugis administered, the average load of the non-resistant bacteria willdecrease and eventually (after 6 weeks of the model's simulation)reach a very low level. However, the average load of drug-resistantbacteria will initially decrease, after treatment, but will laterbounce back and remain at a high level. This level can be made lowerif larger amount of drug is given or if the contact between healthcare workers and patients is reduced. |
| format | Article |
| id | doaj-art-ae2c05064fed461686e2311d9ecc03f7 |
| institution | Kabale University |
| issn | 1551-0018 |
| language | English |
| publishDate | 2010-09-01 |
| publisher | AIMS Press |
| record_format | Article |
| series | Mathematical Biosciences and Engineering |
| spelling | doaj-art-ae2c05064fed461686e2311d9ecc03f72025-01-24T02:00:58ZengAIMS PressMathematical Biosciences and Engineering1551-00182010-09-017477979210.3934/mbe.2010.7.779A model of drug resistance with infection by health care workersAvner Friedman0Najat Ziyadi1Khalid Boushaba2The Ohio State University, Department of Mathematics, Columbus, OH 43210The Ohio State University, Department of Mathematics, Columbus, OH 43210The Ohio State University, Department of Mathematics, Columbus, OH 43210Antibiotic resistant organisms (ARO) pose an increasing seriousthreat in hospitals. One of the most life threatening ARO ismethicillin-resistant staphylococcus aureus (MRSA). In this paper,we introduced a new mathematical model which focuses on theevolution of two bacterial strains, drug-resistant and non-drugresistant, residing within the population of patients and healthcare workers in a hospital. The model predicts that as soon as drugis administered, the average load of the non-resistant bacteria willdecrease and eventually (after 6 weeks of the model's simulation)reach a very low level. However, the average load of drug-resistantbacteria will initially decrease, after treatment, but will laterbounce back and remain at a high level. This level can be made lowerif larger amount of drug is given or if the contact between healthcare workers and patients is reduced.https://www.aimspress.com/article/doi/10.3934/mbe.2010.7.779infection in hospitaldrug resistant bacteriahealth care workers. |
| spellingShingle | Avner Friedman Najat Ziyadi Khalid Boushaba A model of drug resistance with infection by health care workers Mathematical Biosciences and Engineering infection in hospital drug resistant bacteria health care workers. |
| title | A model of drug resistance with infection by health care workers |
| title_full | A model of drug resistance with infection by health care workers |
| title_fullStr | A model of drug resistance with infection by health care workers |
| title_full_unstemmed | A model of drug resistance with infection by health care workers |
| title_short | A model of drug resistance with infection by health care workers |
| title_sort | model of drug resistance with infection by health care workers |
| topic | infection in hospital drug resistant bacteria health care workers. |
| url | https://www.aimspress.com/article/doi/10.3934/mbe.2010.7.779 |
| work_keys_str_mv | AT avnerfriedman amodelofdrugresistancewithinfectionbyhealthcareworkers AT najatziyadi amodelofdrugresistancewithinfectionbyhealthcareworkers AT khalidboushaba amodelofdrugresistancewithinfectionbyhealthcareworkers AT avnerfriedman modelofdrugresistancewithinfectionbyhealthcareworkers AT najatziyadi modelofdrugresistancewithinfectionbyhealthcareworkers AT khalidboushaba modelofdrugresistancewithinfectionbyhealthcareworkers |