A model of drug resistance with infection by health care workers
Antibiotic resistant organisms (ARO) pose an increasing seriousthreat in hospitals. One of the most life threatening ARO ismethicillin-resistant staphylococcus aureus (MRSA). In this paper,we introduced a new mathematical model which focuses on theevolution of two bacterial strains, drug-resistant a...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
AIMS Press
2010-09-01
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| Series: | Mathematical Biosciences and Engineering |
| Subjects: | |
| Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2010.7.779 |
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| Summary: | Antibiotic resistant organisms (ARO) pose an increasing seriousthreat in hospitals. One of the most life threatening ARO ismethicillin-resistant staphylococcus aureus (MRSA). In this paper,we introduced a new mathematical model which focuses on theevolution of two bacterial strains, drug-resistant and non-drugresistant, residing within the population of patients and healthcare workers in a hospital. The model predicts that as soon as drugis administered, the average load of the non-resistant bacteria willdecrease and eventually (after 6 weeks of the model's simulation)reach a very low level. However, the average load of drug-resistantbacteria will initially decrease, after treatment, but will laterbounce back and remain at a high level. This level can be made lowerif larger amount of drug is given or if the contact between healthcare workers and patients is reduced. |
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| ISSN: | 1551-0018 |