ANA Negative Systemic Lupus Erythematosus Leading to CTEPH, TTP-Like Thrombocytopenia, and Skin Ulcers

SLE affects almost every organ system, with differing degrees of severity. During its clinical course periods of flares may alternate with periods of remission culminating in disease and therapy related damage. We describe a case of ANA negative SLE with severe thrombocytopenia, cutaneous vasculitis...

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Main Authors: Khalid Hamid Changal, Fayaz Sofi, Sheikh Shoaib Altaf, Adnan Raina, Ab. Hameed Raina
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2016/4507247
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author Khalid Hamid Changal
Fayaz Sofi
Sheikh Shoaib Altaf
Adnan Raina
Ab. Hameed Raina
author_facet Khalid Hamid Changal
Fayaz Sofi
Sheikh Shoaib Altaf
Adnan Raina
Ab. Hameed Raina
author_sort Khalid Hamid Changal
collection DOAJ
description SLE affects almost every organ system, with differing degrees of severity. During its clinical course periods of flares may alternate with periods of remission culminating in disease and therapy related damage. We describe a case of ANA negative SLE with severe thrombocytopenia, cutaneous vasculitis, antiphospholipid antibody syndrome, and pulmonary artery hypertension. As there is no definitive cure for SLE the treatment lies in caring for the individual organ systems involved and simultaneously taking care of the patient as a whole.
format Article
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institution Kabale University
issn 2090-6889
2090-6897
language English
publishDate 2016-01-01
publisher Wiley
record_format Article
series Case Reports in Rheumatology
spelling doaj-art-ae225944bebc48aeb4792cd34c1018af2025-02-03T06:11:32ZengWileyCase Reports in Rheumatology2090-68892090-68972016-01-01201610.1155/2016/45072474507247ANA Negative Systemic Lupus Erythematosus Leading to CTEPH, TTP-Like Thrombocytopenia, and Skin UlcersKhalid Hamid Changal0Fayaz Sofi1Sheikh Shoaib Altaf2Adnan Raina3Ab. Hameed Raina4Internal Medicine, Sher-I-Kashmir Institute of Medical Sciences, Srinagar 190011, IndiaRheumatology and Internal Medicine, Sher-I-Kashmir Institute of Medical Sciences, Srinagar 190011, IndiaInternal Medicine, Mercy Catholic Medical Center, Philadelphia, PA 19026, USAInternal Medicine, Sher-I-Kashmir Institute of Medical Sciences, Srinagar 190011, IndiaInternal Medicine, Sher-I-Kashmir Institute of Medical Sciences, Srinagar 190011, IndiaSLE affects almost every organ system, with differing degrees of severity. During its clinical course periods of flares may alternate with periods of remission culminating in disease and therapy related damage. We describe a case of ANA negative SLE with severe thrombocytopenia, cutaneous vasculitis, antiphospholipid antibody syndrome, and pulmonary artery hypertension. As there is no definitive cure for SLE the treatment lies in caring for the individual organ systems involved and simultaneously taking care of the patient as a whole.http://dx.doi.org/10.1155/2016/4507247
spellingShingle Khalid Hamid Changal
Fayaz Sofi
Sheikh Shoaib Altaf
Adnan Raina
Ab. Hameed Raina
ANA Negative Systemic Lupus Erythematosus Leading to CTEPH, TTP-Like Thrombocytopenia, and Skin Ulcers
Case Reports in Rheumatology
title ANA Negative Systemic Lupus Erythematosus Leading to CTEPH, TTP-Like Thrombocytopenia, and Skin Ulcers
title_full ANA Negative Systemic Lupus Erythematosus Leading to CTEPH, TTP-Like Thrombocytopenia, and Skin Ulcers
title_fullStr ANA Negative Systemic Lupus Erythematosus Leading to CTEPH, TTP-Like Thrombocytopenia, and Skin Ulcers
title_full_unstemmed ANA Negative Systemic Lupus Erythematosus Leading to CTEPH, TTP-Like Thrombocytopenia, and Skin Ulcers
title_short ANA Negative Systemic Lupus Erythematosus Leading to CTEPH, TTP-Like Thrombocytopenia, and Skin Ulcers
title_sort ana negative systemic lupus erythematosus leading to cteph ttp like thrombocytopenia and skin ulcers
url http://dx.doi.org/10.1155/2016/4507247
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