XPR1 promotes ovarian cancer growth and regulates MHC-I through autophagy

XPR1 promotes ovarian cancer growth and regulates MHC-I through autophagy

Immune checkpoint inhibitors have a poor effect in treating ovarian cancer, and the specific mechanism is unknown. The purpose of this research was to investigate the impact of XPR1 on controlling autophagy in ovarian cancer. The findings suggested an increase in XPR1 expression in ovarian cancer ti...

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Bibliographic Details
Main Authors: Hui Wang, Xiaodong Luo, Bo Yang, Furong Tang, Xingwei Jiang, Hongtao Zhu, Jianguo Hu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-09-01
Series:Genes and Diseases
Subjects:
Autophagy
LAMP1
MHC-1
Ovarian cancer
XPR1
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304224003040
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