Anthropometric Indices of Obesity and the Prediction of Cardiovascular Risk Factors in an Iranian Population

The prevalence of hypertension, diabetes, dyslipidemia, and metabolic syndrome are increasing globally. The present study was conducted in an attempt to define optimal cutoff values for several anthropometric variables in an Iranian population, as these may vary with ethnicity. Iranian subjects (248...

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Main Authors: Mohsen Azimi–Nezhad, Majid Ghayour–Mobarhan, Mohammad Safarian, Habibollah Esmailee, Seyed Mohammad Reza Parizadeh, Maryam Rajabi-Moghadam, Arezoo Gholami, Mohammad Reza Oladi, Gordon A. Ferns
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2009.58
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author Mohsen Azimi–Nezhad
Majid Ghayour–Mobarhan
Mohammad Safarian
Habibollah Esmailee
Seyed Mohammad Reza Parizadeh
Maryam Rajabi-Moghadam
Arezoo Gholami
Mohammad Reza Oladi
Gordon A. Ferns
author_facet Mohsen Azimi–Nezhad
Majid Ghayour–Mobarhan
Mohammad Safarian
Habibollah Esmailee
Seyed Mohammad Reza Parizadeh
Maryam Rajabi-Moghadam
Arezoo Gholami
Mohammad Reza Oladi
Gordon A. Ferns
author_sort Mohsen Azimi–Nezhad
collection DOAJ
description The prevalence of hypertension, diabetes, dyslipidemia, and metabolic syndrome are increasing globally. The present study was conducted in an attempt to define optimal cutoff values for several anthropometric variables in an Iranian population, as these may vary with ethnicity. Iranian subjects (2483 men and 2445 women), aged 15–65 years, were recruited using a cluster-stratified sampling method from rural and urban areas within the Khorasan province. Receiver operating characteristics (ROC) analysis was used to define optimal anthropometric cutoff values. The prevalence of hypertension, diabetes, dyslipidemia, and metabolic syndrome were 28, 5.5, 67, and 39.9%, respectively. The gender-specific cutoff values for waist:height ratio to predict hypertension, diabetes, dyslipidemia, and metabolic syndrome among men were 0.52 (sensitivity = 66%; specificity = 66%), 0.54 (sensitivity = 65%; specificity = 65%), 0.50 (sensitivity = 58%; specificity = 57%), and 0.53 (sensitivity = 73%; specificity = 70%), and for women were 0.59 (sensitivity = 61%; specificity = 61%), 0.61 (sensitivity = 64%; specificity = 64%), 0.57 (sensitivity = 61%; specificity = 61%), and 0.59 (sensitivity = 77%; specificity = 77%) (p < 0.05). Significant correlations were found between waist:height ratio and hypertension, diabetes mellitus, dyslipidemia, and metabolic syndrome, particularly in women. Waist circumference cutoffs were higher for women than men for hypertension, diabetes mellitus, and dyslipidemia.
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spelling doaj-art-adf5c4702bb24c90a8891b1046b856e92025-02-03T06:05:58ZengWileyThe Scientific World Journal1537-744X2009-01-01942443010.1100/tsw.2009.58Anthropometric Indices of Obesity and the Prediction of Cardiovascular Risk Factors in an Iranian PopulationMohsen Azimi–Nezhad0Majid Ghayour–Mobarhan1Mohammad Safarian2Habibollah Esmailee3Seyed Mohammad Reza Parizadeh4Maryam Rajabi-Moghadam5Arezoo Gholami6Mohammad Reza Oladi7Gordon A. Ferns8Department of Biochemistry and Nutrition, Mashhad University of Medical Sciences (MUMS), Mashhad, Islamic Republic of IranDepartment of Biochemistry and Nutrition, Mashhad University of Medical Sciences (MUMS), Mashhad, Islamic Republic of IranDepartment of Biochemistry and Nutrition, Mashhad University of Medical Sciences (MUMS), Mashhad, Islamic Republic of IranCommunity Health and Statistic Department, Mashhad University of Medical Sciences (MUMS), Mashhad, Islamic Republic of IranDepartment of Biochemistry and Nutrition, Mashhad University of Medical Sciences (MUMS), Mashhad, Islamic Republic of IranCardiovascular Research Center, Avicenna Research Institute, Mashhad University of Medical Sciences (MUMS), Mashhad, Islamic Republic of IranCardiovascular Research Center, Avicenna Research Institute, Mashhad University of Medical Sciences (MUMS), Mashhad, Islamic Republic of IranPharmacutical Research Center, Avicenna Research Institute, Faculty of Medicine, Mashhad University of Medical Sciences (MUMS), Mashhad, Islamic Republic of IranPostgraduate Medical School, University of Surrey, Stag Hill, UkThe prevalence of hypertension, diabetes, dyslipidemia, and metabolic syndrome are increasing globally. The present study was conducted in an attempt to define optimal cutoff values for several anthropometric variables in an Iranian population, as these may vary with ethnicity. Iranian subjects (2483 men and 2445 women), aged 15–65 years, were recruited using a cluster-stratified sampling method from rural and urban areas within the Khorasan province. Receiver operating characteristics (ROC) analysis was used to define optimal anthropometric cutoff values. The prevalence of hypertension, diabetes, dyslipidemia, and metabolic syndrome were 28, 5.5, 67, and 39.9%, respectively. The gender-specific cutoff values for waist:height ratio to predict hypertension, diabetes, dyslipidemia, and metabolic syndrome among men were 0.52 (sensitivity = 66%; specificity = 66%), 0.54 (sensitivity = 65%; specificity = 65%), 0.50 (sensitivity = 58%; specificity = 57%), and 0.53 (sensitivity = 73%; specificity = 70%), and for women were 0.59 (sensitivity = 61%; specificity = 61%), 0.61 (sensitivity = 64%; specificity = 64%), 0.57 (sensitivity = 61%; specificity = 61%), and 0.59 (sensitivity = 77%; specificity = 77%) (p < 0.05). Significant correlations were found between waist:height ratio and hypertension, diabetes mellitus, dyslipidemia, and metabolic syndrome, particularly in women. Waist circumference cutoffs were higher for women than men for hypertension, diabetes mellitus, and dyslipidemia.http://dx.doi.org/10.1100/tsw.2009.58
spellingShingle Mohsen Azimi–Nezhad
Majid Ghayour–Mobarhan
Mohammad Safarian
Habibollah Esmailee
Seyed Mohammad Reza Parizadeh
Maryam Rajabi-Moghadam
Arezoo Gholami
Mohammad Reza Oladi
Gordon A. Ferns
Anthropometric Indices of Obesity and the Prediction of Cardiovascular Risk Factors in an Iranian Population
The Scientific World Journal
title Anthropometric Indices of Obesity and the Prediction of Cardiovascular Risk Factors in an Iranian Population
title_full Anthropometric Indices of Obesity and the Prediction of Cardiovascular Risk Factors in an Iranian Population
title_fullStr Anthropometric Indices of Obesity and the Prediction of Cardiovascular Risk Factors in an Iranian Population
title_full_unstemmed Anthropometric Indices of Obesity and the Prediction of Cardiovascular Risk Factors in an Iranian Population
title_short Anthropometric Indices of Obesity and the Prediction of Cardiovascular Risk Factors in an Iranian Population
title_sort anthropometric indices of obesity and the prediction of cardiovascular risk factors in an iranian population
url http://dx.doi.org/10.1100/tsw.2009.58
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