Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis

A patient with congenital insensitivity to pain with anhidrosis (CIPA) underwent revision of total hip arthroplasty under general anesthesia with only propofol. During surgery, neither elevation of stress hormones nor hemodynamic changes associated with pain occurred; however, when blood was rapidly...

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Main Authors: Yuki Sugiyama, Sayako Gotoh, Masatoshi Urasawa, Mikito Kawamata, Koichi Nakajima
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Anesthesiology
Online Access:http://dx.doi.org/10.1155/2018/9593458
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author Yuki Sugiyama
Sayako Gotoh
Masatoshi Urasawa
Mikito Kawamata
Koichi Nakajima
author_facet Yuki Sugiyama
Sayako Gotoh
Masatoshi Urasawa
Mikito Kawamata
Koichi Nakajima
author_sort Yuki Sugiyama
collection DOAJ
description A patient with congenital insensitivity to pain with anhidrosis (CIPA) underwent revision of total hip arthroplasty under general anesthesia with only propofol. During surgery, neither elevation of stress hormones nor hemodynamic changes associated with pain occurred; however, when blood was rapidly lost, compensatory tachycardia was observed. Although patients with CIPA are complicated with autonomic disturbance due to dysfunction of postganglionic sympathetic fibers, this compensatory response indicated that the adrenal glands in patients with CIPA secrete catecholamine as part of a compensatory response during bleeding under general anesthesia.
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institution Kabale University
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publishDate 2018-01-01
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series Case Reports in Anesthesiology
spelling doaj-art-adf10463cc8a4713a71ecc09f73eda0a2025-02-03T01:26:08ZengWileyCase Reports in Anesthesiology2090-63822090-63902018-01-01201810.1155/2018/95934589593458Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with AnhidrosisYuki Sugiyama0Sayako Gotoh1Masatoshi Urasawa2Mikito Kawamata3Koichi Nakajima4Department of Anesthesiology and Resuscitology, Shinshu University School of Medicine, JapanDepartment of Anesthesiology and Resuscitology, Shinshu University School of Medicine, JapanDepartment of Anesthesiology and Resuscitology, Shinshu University School of Medicine, JapanDepartment of Anesthesiology and Resuscitology, Shinshu University School of Medicine, JapanDivision of Anesthesia, Shinonoi General Hospital, JapanA patient with congenital insensitivity to pain with anhidrosis (CIPA) underwent revision of total hip arthroplasty under general anesthesia with only propofol. During surgery, neither elevation of stress hormones nor hemodynamic changes associated with pain occurred; however, when blood was rapidly lost, compensatory tachycardia was observed. Although patients with CIPA are complicated with autonomic disturbance due to dysfunction of postganglionic sympathetic fibers, this compensatory response indicated that the adrenal glands in patients with CIPA secrete catecholamine as part of a compensatory response during bleeding under general anesthesia.http://dx.doi.org/10.1155/2018/9593458
spellingShingle Yuki Sugiyama
Sayako Gotoh
Masatoshi Urasawa
Mikito Kawamata
Koichi Nakajima
Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis
Case Reports in Anesthesiology
title Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis
title_full Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis
title_fullStr Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis
title_full_unstemmed Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis
title_short Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis
title_sort hemodynamic response to massive bleeding in a patient with congenital insensitivity to pain with anhidrosis
url http://dx.doi.org/10.1155/2018/9593458
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AT mikitokawamata hemodynamicresponsetomassivebleedinginapatientwithcongenitalinsensitivitytopainwithanhidrosis
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