Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis
A patient with congenital insensitivity to pain with anhidrosis (CIPA) underwent revision of total hip arthroplasty under general anesthesia with only propofol. During surgery, neither elevation of stress hormones nor hemodynamic changes associated with pain occurred; however, when blood was rapidly...
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Format: | Article |
Language: | English |
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Wiley
2018-01-01
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Series: | Case Reports in Anesthesiology |
Online Access: | http://dx.doi.org/10.1155/2018/9593458 |
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author | Yuki Sugiyama Sayako Gotoh Masatoshi Urasawa Mikito Kawamata Koichi Nakajima |
author_facet | Yuki Sugiyama Sayako Gotoh Masatoshi Urasawa Mikito Kawamata Koichi Nakajima |
author_sort | Yuki Sugiyama |
collection | DOAJ |
description | A patient with congenital insensitivity to pain with anhidrosis (CIPA) underwent revision of total hip arthroplasty under general anesthesia with only propofol. During surgery, neither elevation of stress hormones nor hemodynamic changes associated with pain occurred; however, when blood was rapidly lost, compensatory tachycardia was observed. Although patients with CIPA are complicated with autonomic disturbance due to dysfunction of postganglionic sympathetic fibers, this compensatory response indicated that the adrenal glands in patients with CIPA secrete catecholamine as part of a compensatory response during bleeding under general anesthesia. |
format | Article |
id | doaj-art-adf10463cc8a4713a71ecc09f73eda0a |
institution | Kabale University |
issn | 2090-6382 2090-6390 |
language | English |
publishDate | 2018-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Anesthesiology |
spelling | doaj-art-adf10463cc8a4713a71ecc09f73eda0a2025-02-03T01:26:08ZengWileyCase Reports in Anesthesiology2090-63822090-63902018-01-01201810.1155/2018/95934589593458Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with AnhidrosisYuki Sugiyama0Sayako Gotoh1Masatoshi Urasawa2Mikito Kawamata3Koichi Nakajima4Department of Anesthesiology and Resuscitology, Shinshu University School of Medicine, JapanDepartment of Anesthesiology and Resuscitology, Shinshu University School of Medicine, JapanDepartment of Anesthesiology and Resuscitology, Shinshu University School of Medicine, JapanDepartment of Anesthesiology and Resuscitology, Shinshu University School of Medicine, JapanDivision of Anesthesia, Shinonoi General Hospital, JapanA patient with congenital insensitivity to pain with anhidrosis (CIPA) underwent revision of total hip arthroplasty under general anesthesia with only propofol. During surgery, neither elevation of stress hormones nor hemodynamic changes associated with pain occurred; however, when blood was rapidly lost, compensatory tachycardia was observed. Although patients with CIPA are complicated with autonomic disturbance due to dysfunction of postganglionic sympathetic fibers, this compensatory response indicated that the adrenal glands in patients with CIPA secrete catecholamine as part of a compensatory response during bleeding under general anesthesia.http://dx.doi.org/10.1155/2018/9593458 |
spellingShingle | Yuki Sugiyama Sayako Gotoh Masatoshi Urasawa Mikito Kawamata Koichi Nakajima Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis Case Reports in Anesthesiology |
title | Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis |
title_full | Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis |
title_fullStr | Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis |
title_full_unstemmed | Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis |
title_short | Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis |
title_sort | hemodynamic response to massive bleeding in a patient with congenital insensitivity to pain with anhidrosis |
url | http://dx.doi.org/10.1155/2018/9593458 |
work_keys_str_mv | AT yukisugiyama hemodynamicresponsetomassivebleedinginapatientwithcongenitalinsensitivitytopainwithanhidrosis AT sayakogotoh hemodynamicresponsetomassivebleedinginapatientwithcongenitalinsensitivitytopainwithanhidrosis AT masatoshiurasawa hemodynamicresponsetomassivebleedinginapatientwithcongenitalinsensitivitytopainwithanhidrosis AT mikitokawamata hemodynamicresponsetomassivebleedinginapatientwithcongenitalinsensitivitytopainwithanhidrosis AT koichinakajima hemodynamicresponsetomassivebleedinginapatientwithcongenitalinsensitivitytopainwithanhidrosis |