Efficient Probabilistic and Geometric Anatomical Mapping Using Particle Mesh Approximation on GPUs

Deformable image registration in the presence of considerable contrast differences and large size and shape changes presents significant research challenges. First, it requires a robust registration framework that does not depend on intensity measurements and can handle large nonlinear shape variati...

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Main Authors: Linh Ha, Marcel Prastawa, Guido Gerig, John H. Gilmore, Cláudio T. Silva, Sarang Joshi
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2011/572187
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author Linh Ha
Marcel Prastawa
Guido Gerig
John H. Gilmore
Cláudio T. Silva
Sarang Joshi
author_facet Linh Ha
Marcel Prastawa
Guido Gerig
John H. Gilmore
Cláudio T. Silva
Sarang Joshi
author_sort Linh Ha
collection DOAJ
description Deformable image registration in the presence of considerable contrast differences and large size and shape changes presents significant research challenges. First, it requires a robust registration framework that does not depend on intensity measurements and can handle large nonlinear shape variations. Second, it involves the expensive computation of nonlinear deformations with high degrees of freedom. Often it takes a significant amount of computation time and thus becomes infeasible for practical purposes. In this paper, we present a solution based on two key ideas: a new registration method that generates a mapping between anatomies represented as a multicompartment model of class posterior images and geometries and an implementation of the algorithm using particle mesh approximation on Graphical Processing Units (GPUs) to fulfill the computational requirements. We show results on the registrations of neonatal to 2-year old infant MRIs. Quantitative validation demonstrates that our proposed method generates registrations that better maintain the consistency of anatomical structures over time and provides transformations that better preserve structures undergoing large deformations than transformations obtained by standard intensity-only registration. We also achieve the speedup of three orders of magnitudes compared to a CPU reference implementation, making it possible to use the technique in time-critical applications.
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issn 1687-4188
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publishDate 2011-01-01
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series International Journal of Biomedical Imaging
spelling doaj-art-adcb8d9a6e1e4d4d995ef35fd540f9872025-02-03T06:11:12ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962011-01-01201110.1155/2011/572187572187Efficient Probabilistic and Geometric Anatomical Mapping Using Particle Mesh Approximation on GPUsLinh Ha0Marcel Prastawa1Guido Gerig2John H. Gilmore3Cláudio T. Silva4Sarang Joshi5Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, UT 84112, USAScientific Computing and Imaging Institute, University of Utah, Salt Lake City, UT 84112, USAScientific Computing and Imaging Institute, University of Utah, Salt Lake City, UT 84112, USADepartment of Psychiatry, University of North Carolina, Chapel Hill, NC 27599, USAScientific Computing and Imaging Institute, University of Utah, Salt Lake City, UT 84112, USAScientific Computing and Imaging Institute, University of Utah, Salt Lake City, UT 84112, USADeformable image registration in the presence of considerable contrast differences and large size and shape changes presents significant research challenges. First, it requires a robust registration framework that does not depend on intensity measurements and can handle large nonlinear shape variations. Second, it involves the expensive computation of nonlinear deformations with high degrees of freedom. Often it takes a significant amount of computation time and thus becomes infeasible for practical purposes. In this paper, we present a solution based on two key ideas: a new registration method that generates a mapping between anatomies represented as a multicompartment model of class posterior images and geometries and an implementation of the algorithm using particle mesh approximation on Graphical Processing Units (GPUs) to fulfill the computational requirements. We show results on the registrations of neonatal to 2-year old infant MRIs. Quantitative validation demonstrates that our proposed method generates registrations that better maintain the consistency of anatomical structures over time and provides transformations that better preserve structures undergoing large deformations than transformations obtained by standard intensity-only registration. We also achieve the speedup of three orders of magnitudes compared to a CPU reference implementation, making it possible to use the technique in time-critical applications.http://dx.doi.org/10.1155/2011/572187
spellingShingle Linh Ha
Marcel Prastawa
Guido Gerig
John H. Gilmore
Cláudio T. Silva
Sarang Joshi
Efficient Probabilistic and Geometric Anatomical Mapping Using Particle Mesh Approximation on GPUs
International Journal of Biomedical Imaging
title Efficient Probabilistic and Geometric Anatomical Mapping Using Particle Mesh Approximation on GPUs
title_full Efficient Probabilistic and Geometric Anatomical Mapping Using Particle Mesh Approximation on GPUs
title_fullStr Efficient Probabilistic and Geometric Anatomical Mapping Using Particle Mesh Approximation on GPUs
title_full_unstemmed Efficient Probabilistic and Geometric Anatomical Mapping Using Particle Mesh Approximation on GPUs
title_short Efficient Probabilistic and Geometric Anatomical Mapping Using Particle Mesh Approximation on GPUs
title_sort efficient probabilistic and geometric anatomical mapping using particle mesh approximation on gpus
url http://dx.doi.org/10.1155/2011/572187
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