Electrospinning in promoting chronic wound healing: materials, process, and applications
In the field of wound treatment, chronic wounds pose a significant burden on the medical system, affecting millions of patients annually. Current treatment methods often fall short in promoting effective wound healing, highlighting the need for innovative approaches. Electrospinning, a technique tha...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-03-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2025.1550553/full |
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| author | Jiaxi Kou Yaodong Li Chen Zhou Xiyu Wang Jian Ni Yue Lin Huaqiang Ge Dongfeng Zheng Guopu Chen Xitai Sun Qian Tan Qian Tan |
| author_facet | Jiaxi Kou Yaodong Li Chen Zhou Xiyu Wang Jian Ni Yue Lin Huaqiang Ge Dongfeng Zheng Guopu Chen Xitai Sun Qian Tan Qian Tan |
| author_sort | Jiaxi Kou |
| collection | DOAJ |
| description | In the field of wound treatment, chronic wounds pose a significant burden on the medical system, affecting millions of patients annually. Current treatment methods often fall short in promoting effective wound healing, highlighting the need for innovative approaches. Electrospinning, a technique that has garnered increasing attention in recent years, shows promise in wound care due to its unique characteristics and advantages. Recent studies have explored the use of electrospun nanofibers in wound healing, demonstrating their efficacy in promoting cell growth and tissue regeneration. Researchers have investigated various materials for electrospinning, including polymers, ceramics, carbon nanotubes (CNTs), and metals. Hydrogel, as a biomaterial that has been widely studied in recent years, has the characteristics of a cell matrix. When combined with electrospinning, it can be used to develop wound dressings with multiple functions. This article is a review of the application of electrospinning technology in the field of wound treatment. It introduces the current research status in the areas of wound pathophysiology, electrospinning preparation technology, and dressing development, hoping to provide references and directions for future research. |
| format | Article |
| id | doaj-art-adb68cfa749d4bbd861d80ffa2cf6bbf |
| institution | DOAJ |
| issn | 2296-4185 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj-art-adb68cfa749d4bbd861d80ffa2cf6bbf2025-08-20T03:16:26ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852025-03-011310.3389/fbioe.2025.15505531550553Electrospinning in promoting chronic wound healing: materials, process, and applicationsJiaxi Kou0Yaodong Li1Chen Zhou2Xiyu Wang3Jian Ni4Yue Lin5Huaqiang Ge6Dongfeng Zheng7Guopu Chen8Xitai Sun9Qian Tan10Qian Tan11Department of Burns and Plastic Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, ChinaDepartment of Burns and Plastic Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, ChinaDepartment of Pancreatic and Metabolic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, ChinaDepartment of Pancreatic and Metabolic Surgery, Medical School of Southeast University, Nanjing Drum Tower Hospital, Nanjing, ChinaDepartment of Burns and Plastic Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, ChinaDepartment of Burns and Plastic Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, ChinaDepartment of Burns and Plastic Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, ChinaDepartment of Burns and Plastic Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, ChinaDepartment of Burns and Plastic Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, ChinaDepartment of Pancreatic and Metabolic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, ChinaDepartment of Burns and Plastic Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, ChinaDepartment of Pancreatic and Metabolic Surgery, Medical School of Southeast University, Nanjing Drum Tower Hospital, Nanjing, ChinaIn the field of wound treatment, chronic wounds pose a significant burden on the medical system, affecting millions of patients annually. Current treatment methods often fall short in promoting effective wound healing, highlighting the need for innovative approaches. Electrospinning, a technique that has garnered increasing attention in recent years, shows promise in wound care due to its unique characteristics and advantages. Recent studies have explored the use of electrospun nanofibers in wound healing, demonstrating their efficacy in promoting cell growth and tissue regeneration. Researchers have investigated various materials for electrospinning, including polymers, ceramics, carbon nanotubes (CNTs), and metals. Hydrogel, as a biomaterial that has been widely studied in recent years, has the characteristics of a cell matrix. When combined with electrospinning, it can be used to develop wound dressings with multiple functions. This article is a review of the application of electrospinning technology in the field of wound treatment. It introduces the current research status in the areas of wound pathophysiology, electrospinning preparation technology, and dressing development, hoping to provide references and directions for future research.https://www.frontiersin.org/articles/10.3389/fbioe.2025.1550553/fullelectrospinninghydrogelnanofiberwound healingdressing |
| spellingShingle | Jiaxi Kou Yaodong Li Chen Zhou Xiyu Wang Jian Ni Yue Lin Huaqiang Ge Dongfeng Zheng Guopu Chen Xitai Sun Qian Tan Qian Tan Electrospinning in promoting chronic wound healing: materials, process, and applications Frontiers in Bioengineering and Biotechnology electrospinning hydrogel nanofiber wound healing dressing |
| title | Electrospinning in promoting chronic wound healing: materials, process, and applications |
| title_full | Electrospinning in promoting chronic wound healing: materials, process, and applications |
| title_fullStr | Electrospinning in promoting chronic wound healing: materials, process, and applications |
| title_full_unstemmed | Electrospinning in promoting chronic wound healing: materials, process, and applications |
| title_short | Electrospinning in promoting chronic wound healing: materials, process, and applications |
| title_sort | electrospinning in promoting chronic wound healing materials process and applications |
| topic | electrospinning hydrogel nanofiber wound healing dressing |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2025.1550553/full |
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