MHCI trafficking signal‐based mRNA vaccines strengthening immune protection against RNA viruses

MHCI trafficking signal‐based mRNA vaccines strengthening immune protection against RNA viruses

Abstract The major histocompatibility complex class I (MHCI) trafficking signal (MITD) plays a pivotal role in enhancing the efficacy of mRNA vaccines. However, there was a lack of research investigating its efficacy in enhancing immune responses to RNA virus infections. Here, we have developed an i...

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Main Authors: Yupei Zhang, Songhui Zhai, Shugang Qin, Yuting Chen, Kepan Chen, Zhiying Huang, Xing Lan, Yaoyao Luo, Guohong Li, Hao Li, Xi He, Meiwan Chen, Zhongwei Zhang, Xingchen Peng, Xin Jiang, Hai Huang, Xiangrong Song
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Bioengineering & Translational Medicine
Subjects:
framework
immune protection
MITD
mRNA vaccines
RNA virus
Online Access:https://doi.org/10.1002/btm2.10709
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