Evaluating data requirements for high-quality haplotype-resolved genomes for creating robust pangenome references

Abstract Background Long-read technologies from Pacific Biosciences (PacBio) and Oxford Nanopore Technologies (ONT) have transformed genomics research by providing diverse data types like HiFi, Duplex, and ultra-long ONT. Despite recent strides in achieving haplotype-phased gapless genome assemblies...

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Bibliographic Details
Main Authors: Prasad Sarashetti, Josipa Lipovac, Filip Tomas, Mile Šikić, Jianjun Liu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-024-03452-y
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