The association between low-concentration heavy metal exposure and chronic kidney disease risk through α-klotho

The association between low-concentration heavy metal exposure and chronic kidney disease risk through α-klotho

Abstract Although the association between pollution exposure and chronic kidney disease (CKD) has been explored, previous studies have focused on specific effects observed via in vitro or animal experiments. We first conducted a priority screening of pollutants for population CKD risk by using machi...

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Bibliographic Details
Main Authors: Sishi Liu, Hao Wang, Yifei Cao, Liping Lu, Yinyin Wu, Fuzhi Lian, Jun Yang, Qin Song
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Low concentration
Metals
Chronic kidney disease (CKD)
Joint effect
α-Klotho
Mediation
Online Access:https://doi.org/10.1038/s41598-025-96016-4
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https://doi.org/10.1038/s41598-025-96016-4

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