Polysialic acid is upregulated on activated immune cells and negatively regulates anticancer immune activity
Suppression of anticancer immune function is a key driver of tumorigenesis. Identifying molecular pathways that inhibit anticancer immunity is critical for developing novel immunotherapeutics. One such molecule that has recently been identified is the carbohydrate polysialic acid (polySia), whose ex...
Saved in:
| Main Authors: | Olivia Drummond-Guy, John Daly, Angeline Wu, Natalie Stewart, Katy Milne, Chloe Duff, Brad H. Nelson, Karla C. Williams, Simon Wisnovsky |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-03-01
|
| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1520948/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Role of Glycans in Human Immunity—A Sweet Code
by: Igor Tvaroška
Published: (2025-06-01) -
Intrinsic Immune Response of HBV/HDV-Infected Cells and Corresponding Innate (Like) Immune Cell Activation
by: Christopher Groth, et al.
Published: (2024-11-01) -
Changes in immune status of circulating NK cells in patients with latent tuberculosis infection
by: Shuang Qin, et al.
Published: (2024-08-01) -
The role of γδТ- and NK-сells in immune response
by: Ye. G. Churina, et al.
Published: (2010-10-01) -
IMMUNE DYSFUNCTIONS IN WOMEN WITH INFERTILITY OF UNKNOWN ORIGIN
by: N. A. Khonina, et al.
Published: (2014-07-01)