Anti-inflammatory actions of acupuncture
Acupuncture has a beneficial effect when treating many diseases and painful conditions, and therefore is thought to be useful as a complementary therapy or to replace generally accepted pharmacological intervention. The attributive effect of acupuncture has been investigated in inflammatory diseases...
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Format: | Article |
Language: | English |
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Wiley
2003-01-01
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Series: | Mediators of Inflammation |
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Online Access: | http://dx.doi.org/10.1080/0962935031000114943 |
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author | Freek J. Zijlstra Ineke van den Berg-de Lange Frank J. P. M. Huygen Jan Klein |
author_facet | Freek J. Zijlstra Ineke van den Berg-de Lange Frank J. P. M. Huygen Jan Klein |
author_sort | Freek J. Zijlstra |
collection | DOAJ |
description | Acupuncture has a beneficial effect when treating many diseases and painful conditions, and therefore is thought to be useful as a complementary therapy or to replace generally accepted pharmacological intervention. The attributive effect of acupuncture has been investigated in inflammatory diseases, including asthma, rhinitis, inflammatory bowel disease, rheumatoid arthritis, epicondylitis, complex regional pain syndrome type 1 and vasculitis. Large randomised trials demonstrating the immediate and sustained effect of acupuncture are missing. Mechanisms underlying the ascribed immunosuppressive actions of acupuncture are reviewed in this communication. The acupuncture-controlled release of neuropeptides from nerve endings and subsequent vasodilative and anti-inflammatory effects through calcitonine gene-related peptide is hypothesised. The complex interactions with substance P, the analgesic contribution of β-endorphin and the balance between cell-specific pro-inflammatory and anti-inflammatory cytokines tumour necrosis factor-α and interleukin-10 are discussed. |
format | Article |
id | doaj-art-ad7c596fbcaa4491add49241d984ce53 |
institution | Kabale University |
issn | 0962-9351 1466-1861 |
language | English |
publishDate | 2003-01-01 |
publisher | Wiley |
record_format | Article |
series | Mediators of Inflammation |
spelling | doaj-art-ad7c596fbcaa4491add49241d984ce532025-02-03T01:29:11ZengWileyMediators of Inflammation0962-93511466-18612003-01-01122596910.1080/0962935031000114943Anti-inflammatory actions of acupunctureFreek J. Zijlstra0Ineke van den Berg-de Lange1Frank J. P. M. Huygen2Jan Klein3Department of Anesthesiology, Erasmus Medical Centre, Centre location, P.O. Box 2040, Rotterdam 3000 CA, The NetherlandsDepartment of Anesthesiology, Erasmus Medical Centre, Centre location, P.O. Box 2040, Rotterdam 3000 CA, The NetherlandsDepartment of Anesthesiology, Erasmus Medical Centre, Centre location, P.O. Box 2040, Rotterdam 3000 CA, The NetherlandsDepartment of Anesthesiology, Erasmus Medical Centre, Centre location, P.O. Box 2040, Rotterdam 3000 CA, The NetherlandsAcupuncture has a beneficial effect when treating many diseases and painful conditions, and therefore is thought to be useful as a complementary therapy or to replace generally accepted pharmacological intervention. The attributive effect of acupuncture has been investigated in inflammatory diseases, including asthma, rhinitis, inflammatory bowel disease, rheumatoid arthritis, epicondylitis, complex regional pain syndrome type 1 and vasculitis. Large randomised trials demonstrating the immediate and sustained effect of acupuncture are missing. Mechanisms underlying the ascribed immunosuppressive actions of acupuncture are reviewed in this communication. The acupuncture-controlled release of neuropeptides from nerve endings and subsequent vasodilative and anti-inflammatory effects through calcitonine gene-related peptide is hypothesised. The complex interactions with substance P, the analgesic contribution of β-endorphin and the balance between cell-specific pro-inflammatory and anti-inflammatory cytokines tumour necrosis factor-α and interleukin-10 are discussed.http://dx.doi.org/10.1080/0962935031000114943AcupunctureInflammationNeuropeptidesCytokinesNitric oxide. |
spellingShingle | Freek J. Zijlstra Ineke van den Berg-de Lange Frank J. P. M. Huygen Jan Klein Anti-inflammatory actions of acupuncture Mediators of Inflammation Acupuncture Inflammation Neuropeptides Cytokines Nitric oxide. |
title | Anti-inflammatory actions of acupuncture |
title_full | Anti-inflammatory actions of acupuncture |
title_fullStr | Anti-inflammatory actions of acupuncture |
title_full_unstemmed | Anti-inflammatory actions of acupuncture |
title_short | Anti-inflammatory actions of acupuncture |
title_sort | anti inflammatory actions of acupuncture |
topic | Acupuncture Inflammation Neuropeptides Cytokines Nitric oxide. |
url | http://dx.doi.org/10.1080/0962935031000114943 |
work_keys_str_mv | AT freekjzijlstra antiinflammatoryactionsofacupuncture AT inekevandenbergdelange antiinflammatoryactionsofacupuncture AT frankjpmhuygen antiinflammatoryactionsofacupuncture AT janklein antiinflammatoryactionsofacupuncture |