Anti-inflammatory actions of acupuncture

Acupuncture has a beneficial effect when treating many diseases and painful conditions, and therefore is thought to be useful as a complementary therapy or to replace generally accepted pharmacological intervention. The attributive effect of acupuncture has been investigated in inflammatory diseases...

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Main Authors: Freek J. Zijlstra, Ineke van den Berg-de Lange, Frank J. P. M. Huygen, Jan Klein
Format: Article
Language:English
Published: Wiley 2003-01-01
Series:Mediators of Inflammation
Subjects:
Online Access:http://dx.doi.org/10.1080/0962935031000114943
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author Freek J. Zijlstra
Ineke van den Berg-de Lange
Frank J. P. M. Huygen
Jan Klein
author_facet Freek J. Zijlstra
Ineke van den Berg-de Lange
Frank J. P. M. Huygen
Jan Klein
author_sort Freek J. Zijlstra
collection DOAJ
description Acupuncture has a beneficial effect when treating many diseases and painful conditions, and therefore is thought to be useful as a complementary therapy or to replace generally accepted pharmacological intervention. The attributive effect of acupuncture has been investigated in inflammatory diseases, including asthma, rhinitis, inflammatory bowel disease, rheumatoid arthritis, epicondylitis, complex regional pain syndrome type 1 and vasculitis. Large randomised trials demonstrating the immediate and sustained effect of acupuncture are missing. Mechanisms underlying the ascribed immunosuppressive actions of acupuncture are reviewed in this communication. The acupuncture-controlled release of neuropeptides from nerve endings and subsequent vasodilative and anti-inflammatory effects through calcitonine gene-related peptide is hypothesised. The complex interactions with substance P, the analgesic contribution of β-endorphin and the balance between cell-specific pro-inflammatory and anti-inflammatory cytokines tumour necrosis factor-α and interleukin-10 are discussed.
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series Mediators of Inflammation
spelling doaj-art-ad7c596fbcaa4491add49241d984ce532025-02-03T01:29:11ZengWileyMediators of Inflammation0962-93511466-18612003-01-01122596910.1080/0962935031000114943Anti-inflammatory actions of acupunctureFreek J. Zijlstra0Ineke van den Berg-de Lange1Frank J. P. M. Huygen2Jan Klein3Department of Anesthesiology, Erasmus Medical Centre, Centre location, P.O. Box 2040, Rotterdam 3000 CA, The NetherlandsDepartment of Anesthesiology, Erasmus Medical Centre, Centre location, P.O. Box 2040, Rotterdam 3000 CA, The NetherlandsDepartment of Anesthesiology, Erasmus Medical Centre, Centre location, P.O. Box 2040, Rotterdam 3000 CA, The NetherlandsDepartment of Anesthesiology, Erasmus Medical Centre, Centre location, P.O. Box 2040, Rotterdam 3000 CA, The NetherlandsAcupuncture has a beneficial effect when treating many diseases and painful conditions, and therefore is thought to be useful as a complementary therapy or to replace generally accepted pharmacological intervention. The attributive effect of acupuncture has been investigated in inflammatory diseases, including asthma, rhinitis, inflammatory bowel disease, rheumatoid arthritis, epicondylitis, complex regional pain syndrome type 1 and vasculitis. Large randomised trials demonstrating the immediate and sustained effect of acupuncture are missing. Mechanisms underlying the ascribed immunosuppressive actions of acupuncture are reviewed in this communication. The acupuncture-controlled release of neuropeptides from nerve endings and subsequent vasodilative and anti-inflammatory effects through calcitonine gene-related peptide is hypothesised. The complex interactions with substance P, the analgesic contribution of β-endorphin and the balance between cell-specific pro-inflammatory and anti-inflammatory cytokines tumour necrosis factor-α and interleukin-10 are discussed.http://dx.doi.org/10.1080/0962935031000114943AcupunctureInflammationNeuropeptidesCytokinesNitric oxide.
spellingShingle Freek J. Zijlstra
Ineke van den Berg-de Lange
Frank J. P. M. Huygen
Jan Klein
Anti-inflammatory actions of acupuncture
Mediators of Inflammation
Acupuncture
Inflammation
Neuropeptides
Cytokines
Nitric oxide.
title Anti-inflammatory actions of acupuncture
title_full Anti-inflammatory actions of acupuncture
title_fullStr Anti-inflammatory actions of acupuncture
title_full_unstemmed Anti-inflammatory actions of acupuncture
title_short Anti-inflammatory actions of acupuncture
title_sort anti inflammatory actions of acupuncture
topic Acupuncture
Inflammation
Neuropeptides
Cytokines
Nitric oxide.
url http://dx.doi.org/10.1080/0962935031000114943
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AT inekevandenbergdelange antiinflammatoryactionsofacupuncture
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AT janklein antiinflammatoryactionsofacupuncture