Evaluation of a modified venous excess ultrasound (VExUS) protocol for estimation of venous congestion: a cohort study

Abstract Background Understanding venous congestion is critical to the management of many illnesses, but assessing volume status can be challenging. The current gold standard for volume status assessment of right heart catheterization (RHC) is invasive, costly, and often unavailable. Venous Excess U...

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Main Authors: Katharine C. Martin, Edward A. Gill, Ivor J. Douglas, August A. Longino
Format: Article
Language:English
Published: SpringerOpen 2025-01-01
Series:The Ultrasound Journal
Online Access:https://doi.org/10.1186/s13089-025-00411-x
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author Katharine C. Martin
Edward A. Gill
Ivor J. Douglas
August A. Longino
author_facet Katharine C. Martin
Edward A. Gill
Ivor J. Douglas
August A. Longino
author_sort Katharine C. Martin
collection DOAJ
description Abstract Background Understanding venous congestion is critical to the management of many illnesses, but assessing volume status can be challenging. The current gold standard for volume status assessment of right heart catheterization (RHC) is invasive, costly, and often unavailable. Venous Excess Ultrasound Score (VExUS) is a novel ultrasound protocol for to assessment of venous congestion using the inferior vena cava, hepatic, portal and renal veins. Though there is a much interest in the technique, the renal component of the exam is challenging to acquire. For this reason we aimed to see if a modified VExUS (mVExUS) excluding the kidney component performs similarly to traditional VExUS (tVExUS) for detecting elevated right atrial pressure (RAP) as measured by RHC. Methods A consecutive cohort of 95 patients undergoing RHC had VExUS exams before the procedure. Researchers compared the performance of tVExUS, mVExUS, and inferior vena cava (IVC) diameter in predicting RAP > 12 mmHg. Results The area under the curve (AUC) for detecting elevated RAP was similar for tVExUS (0.87) and mVExUS (0.85). Both methods achieved high sensitivity and specificity. Agreement between tVExUS and mVExUS scores was near-perfect (Cohen's Kappa = 0.85). Conclusion mVExUS may be as effective as tVExUS in identifying elevated RAP. This abbreviated version could improve efficiency and adoption of VExUS for assessing venous congestion. Further studies are needed in diverse patient populations.
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spelling doaj-art-ad7545e79e614b6ca1e0c4696266e22b2025-01-19T12:14:40ZengSpringerOpenThe Ultrasound Journal2524-89872025-01-011711510.1186/s13089-025-00411-xEvaluation of a modified venous excess ultrasound (VExUS) protocol for estimation of venous congestion: a cohort studyKatharine C. Martin0Edward A. Gill1Ivor J. Douglas2August A. Longino3Department of Internal Medicine, University of Colorado HospitalDepartment of Cardiology, University of Colorado HospitalMedicine, Pulmonary Sciences and Critical Care Medicine, University of Colorado Medical School and Denver Health Medical CenterDepartment of Internal Medicine, University of Colorado HospitalAbstract Background Understanding venous congestion is critical to the management of many illnesses, but assessing volume status can be challenging. The current gold standard for volume status assessment of right heart catheterization (RHC) is invasive, costly, and often unavailable. Venous Excess Ultrasound Score (VExUS) is a novel ultrasound protocol for to assessment of venous congestion using the inferior vena cava, hepatic, portal and renal veins. Though there is a much interest in the technique, the renal component of the exam is challenging to acquire. For this reason we aimed to see if a modified VExUS (mVExUS) excluding the kidney component performs similarly to traditional VExUS (tVExUS) for detecting elevated right atrial pressure (RAP) as measured by RHC. Methods A consecutive cohort of 95 patients undergoing RHC had VExUS exams before the procedure. Researchers compared the performance of tVExUS, mVExUS, and inferior vena cava (IVC) diameter in predicting RAP > 12 mmHg. Results The area under the curve (AUC) for detecting elevated RAP was similar for tVExUS (0.87) and mVExUS (0.85). Both methods achieved high sensitivity and specificity. Agreement between tVExUS and mVExUS scores was near-perfect (Cohen's Kappa = 0.85). Conclusion mVExUS may be as effective as tVExUS in identifying elevated RAP. This abbreviated version could improve efficiency and adoption of VExUS for assessing venous congestion. Further studies are needed in diverse patient populations.https://doi.org/10.1186/s13089-025-00411-x
spellingShingle Katharine C. Martin
Edward A. Gill
Ivor J. Douglas
August A. Longino
Evaluation of a modified venous excess ultrasound (VExUS) protocol for estimation of venous congestion: a cohort study
The Ultrasound Journal
title Evaluation of a modified venous excess ultrasound (VExUS) protocol for estimation of venous congestion: a cohort study
title_full Evaluation of a modified venous excess ultrasound (VExUS) protocol for estimation of venous congestion: a cohort study
title_fullStr Evaluation of a modified venous excess ultrasound (VExUS) protocol for estimation of venous congestion: a cohort study
title_full_unstemmed Evaluation of a modified venous excess ultrasound (VExUS) protocol for estimation of venous congestion: a cohort study
title_short Evaluation of a modified venous excess ultrasound (VExUS) protocol for estimation of venous congestion: a cohort study
title_sort evaluation of a modified venous excess ultrasound vexus protocol for estimation of venous congestion a cohort study
url https://doi.org/10.1186/s13089-025-00411-x
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